中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
Construction of colorimetric/fluorescent dual-signal probes for the detection of
β
-galactosidase in senescent cells
期刊论文
OAI收割
DYES AND PIGMENTS, 2025, 卷号: 242, 页码: 8
作者:
Dong, Lei
;
Sun, Lu-Lu
;
Li, Wen-Jia
;
Xing, Jing
;
Tan, Mingchao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
beta-Galactosidase
Fluorescence sensing
Cell senescence
Dislocation loops enhance wear resistance in Ti2Zr0.75NbVx lightweight refractory medium-entropy alloys via high thermal conductivity-promoted oxide film formation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF REFRACTORY METALS & HARD MATERIALS, 2025, 卷号: 132, 页码: 13
作者:
Zhang, Xinlong
;
Xiong, Zixian
;
Li, Lianning
;
Feng, Zhiyu
;
Wu, Bingzhao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/18
Lightweight refractory medium-entropy alloys
Dislocation loops
Thermal conductivity
Wear resistance
Molecular dynamics simulation
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
The dynamic features and microbial mechanism of nitrogen transformation in small greenhouse farming system of Pacific white shrimp,
Litopenaeus vannamei
期刊论文
OAI收割
AQUACULTURE, 2025, 卷号: 605, 页码: 14
作者:
Huang, Yong
;
Liu, Mei
;
Jiang, Keyong
;
Zhong, Chen
;
Xu, Kefeng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/11
Small greenhouse farming system
Denitrification
Nitrification
Surface sediment
Suspended particulate matter
NIR-II Engineered Exosome Nanotheranostic Probes for "Oriented Blasting" in Orthotopic Glioblastoma
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 25, 页码: 22900-22913
作者:
Yu, Donghu
;
Ding, Qihang
;
Xiang, Chunbai
;
Wang, Danwen
;
Hu, Lei
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
glioblastoma
NIR-II
blood-brainbarrier
photothermal therapy
photodynamic therapy
Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth
期刊论文
OAI收割
MOLECULES, 2025, 卷号: 30, 期号: 10, 页码: 22
作者:
Peng, Xia
;
Yu, Siqi
;
Xu, Lin
;
Wang, Qinghua
;
Yang, Lin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/07/25
pseudolaric acid B
amide derivatives
tumor-associated macrophages
anti-tumor
repolarization
Development of
99m
Tc-labeled melanin-targeted probes for SPECT imaging of melanoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 14
作者:
Tao, Ji
;
Cao, Rui
;
Lei, Zhe
;
Wang, Xiao
;
Luo, Renli
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/06/23
Melanoma
Melanin
(99m)Technetium
SPECT
Imaging probe
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:
Hu, Liuyan
;
Zhao, Zhi
;
Zhang, Shujing
;
Yang, Lei
;
Cui, Wenjie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/23
COVID-19
SARS-CoV-2
3CL protease
Peptidomimetic inhibitors
Tetrahydropyrrole spirodihydroindolone
New Phenolic Compounds from
Eucalyptus tereticornis
with Antioxidant Activity
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2025, 页码: 8
作者:
Zhang, Yu
;
Miao, Lei
;
Li, Guo-Li
;
Zhang, Chuan-Rui
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/05/27
antioxidant activity
configuration determination
Eucalyptus tereticornis
glycosides
sesquilignans