机构

• 上海药物研究所 [20]
• 海洋研究所 [1]
• 生态环境研究中心 [1]

采集方式

• OAI收割 [22]

内容类型

• 期刊论文 [22]

发表日期

• 2025 [1]
• 2024 [5]
• 2023 [4]
• 2022 [3]
• 2021 [4]
• 2020 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 25 作者:  Lu, Yuhang;  Yan, Ziqin;  Sun, Jiaqi;  Wang, Chenxu;  Xu, Lan   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/04/01 Structure-Based Drug Design of 2-Amino-[1,1′-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1-Amplified Breast Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Wang, Chaofan;  Fang, Yan;  Zhou, Ziqin;  Liu, Zhuoheng;  Feng, Fang   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/09/26 Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36 作者:  Lou, Jianfeng;  Zhou, Qianqian;  Lyu, Xilin;  Cen, Xinyi;  Liu, Chen   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/08/22 Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 16 作者:  Lin, Zhitong;  Liu, Chen;  Yan, Ziqin;  Cheng, Jing;  Wang, Xiancheng   |  收藏  |  浏览/下载：28/0  |  提交时间：2024/06/27 MDM2  p53  p21  Imidazolidinone  Apoptosis   Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-KB-inducing kinase (NIK) 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1295, 页码: 19 作者:  Cheng, Jing;  Yan, Ziqin;  Li, Xinzhi;  Liu, Chen;  Tong, Linjiang   |  收藏  |  浏览/下载：140/0  |  提交时间：2023/12/08 Kinase inhibitor  NIK  NF-KB2  Indoline  COT  Cytotoxicity   Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092 作者:  Qin, Shaozhao;  Feng, Lijian;  Zhao, Qingyi;  Yan, Ziqin;  Lyu, Xilin   |  收藏  |  浏览/下载：44/0  |  提交时间：2024/02/27 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/02/19 The dinoflagellate Noctiluca scintillans in China: A review of its distribution and role in harmful algal blooms 期刊论文  OAI收割 MARINE POLLUTION BULLETIN, 2023, 卷号: 194, 页码: 30 作者:  Li, Xiaodong;  Lu, Weijing;  Jiang, Fan;  Chen, Ziqin;  Chang, Yang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/12/07 Noctiluca scintillans  Harmful algal blooms  Plankton structure  Succession   Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078 作者:  Seydimemet, Mengnisa;  Yang, Yixuan;  Lv, Yuhan;  Liu, Jiaxiang;  Yan, Ziqin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 DNA-encoded library technology  Pyrimidine-focusedDNA-encodedlibrary  BRD4  Affinity screening  Inhibitor   Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17 作者:  Yan, Ziqin;  Lyu, Xilin;  Lin, Dongze;  Wu, Gaoxing;  Gong, Yang   |  收藏  |  浏览/下载：47/0  |  提交时间：2023/10/17