中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [23]
地理科学与资源研究所 [5]
昆明植物研究所 [4]
遥感与数字地球研究所 [2]
广州生物医药与健康研... [2]
大连化学物理研究所 [2]
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OAI收割 [39]
iSwitch采集 [1]
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期刊论文 [35]
EI期刊论文 [2]
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会议论文 [1]
学位论文 [1]
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2022 [2]
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2020 [1]
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学科主题
Cell Biolo... [2]
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Response of Vegetation Phenology to the Interaction of Temperature and Precipitation Changes in Qilian Mountains
期刊论文
OAI收割
REMOTE SENSING, 2022, 卷号: 14, 期号: 5, 页码: 24
作者:
Li, Cheng
;
Zou, Yuyang
;
He, Jianfeng
;
Zhang, Wen
;
Gao, Lulu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/09/21
climate change
grassland phenology
Qilian Mountains
GeoDetector
earth observation
Response of Vegetation Phenology to the Interaction of Temperature and Precipitation Changes in Qilian Mountains
期刊论文
OAI收割
REMOTE SENSING, 2022, 卷号: 14, 期号: 5, 页码: 24
作者:
Li, Cheng
;
Zou, Yuyang
;
He, Jianfeng
;
Zhang, Wen
;
Gao, Lulu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/09/21
climate change
grassland phenology
Qilian Mountains
GeoDetector
earth observation
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:
Gao, Yuxiong
;
Chen, Zhendong
;
Yang, Changyong
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
Anti-sclerostin monoclonal antibody (SHR-1222)
LC-MS/MS
Anti-drug antibody
Toxicokinetic
Technologies to improve the sensitivity of existing chromatographic methods used for bioanalytical studies
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2020, 卷号: 34, 期号: 3, 页码: 13
作者:
Chen, Zhendong
;
Gao, Yuxiong
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
chromatographic methods
clean-up efficiency
derivatization
high-resolution chromatography
recovery
sensitivity
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
期刊论文
OAI收割
CANCER CELL, 2019, 卷号: 35, 期号: 4, 页码: 677-+
作者:
Huang, Yue
;
Su, Rui
;
Sheng, Yue
;
Dong, Lei
;
Dong, Ze
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
靶向肾癌中的E3连接酶接头蛋白SPOP的小分子抑制剂
期刊论文
OAI收割
科学新闻, 2017, 期号: 04, 页码: 59
作者:
Zhong-Qiang Guo
;
Tong Zheng
;
Baoen Chen
;
Cheng Luo
;
Sisheng Ouyang
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
肾癌
SPOP
透明细胞
肾肿瘤
接头蛋白
E3
Small-molecule targeting of e3 ligase adaptor spop in kidney cancer
期刊论文
iSwitch采集
Cancer cell, 2016, 卷号: 30, 期号: 3, 页码: 474-484
作者:
Guo, Zhong-Qiang
;
Zheng, Tong
;
Chen, Baoen
;
Luo, Cheng
;
Ouyang, Sisheng
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2019/05/09
Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer
期刊论文
OAI收割
CANCER CELL, 2016, 卷号: 30, 期号: 3, 页码: 474-484
作者:
Guo, Zhong-Qiang
;
Zheng, Tong
;
Chen, Baoen
;
Luo, Cheng
;
Ouyang, Sisheng
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
preclinicalpharmacokineticsoftpn729maanovelpde5inhibitorandpredictionofitshumanpharmacokineticsusingapbpkmodel
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1528
作者:
Gao Zhiwei
;
Zhu Yunting
;
Yu Mingming
;
Zan Bin
;
Liu Jia
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
HUMAN DRUG CLEARANCE
PHOSPHODIESTERASE-5 INHIBITORS
CLINICAL PHARMACOKINETICS
ERECTILE DYSFUNCTION
TISSUE DISTRIBUTION
ORAL PHARMACOKINETICS
RECEPTOR ANTAGONIST
DIVERSE COMPOUNDS
IN-VIVO
ABSORPTION
TPN729MA
PDE5 inhibitor
erectile dysfunction
pharmacokinetics
human PK prediction
physiologically based pharmacokinetic model