中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Deciphering the Metabolic Impact and Clinical Relevance of N-Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 15
作者:
Liu, Guobin
;
Chen, Lu
;
Zhao, Jingxiang
;
Jiang, Yue
;
Guo, Yarong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/06/23
clinical relevance
colorectal cancer
functions
glycoproteomics
intact
N
-glycopeptides
Mantle metasomatism by subducted Indian continental crust: Evidence from post-collisional basaltic ultrapotassic rocks in southern Tibetan plateau
期刊论文
OAI收割
LITHOS, 2025, 卷号: 498, 页码: 11
作者:
Zhang, Miao-Yan
;
Hao, Lu-Lu
;
Qi, Yue
;
Wang, Qiang
;
Kerr, Andrew C.
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/04/03
Mo - B isotopes
Post-collisional ultrapotassic rocks
Continental crust recycling
Crust-mantle interaction
Tibetan Plateau
TRPML1 ion channel promotes HepaRG cell differentiation under simulated microgravity conditions
期刊论文
OAI收割
NPJ MICROGRAVITY, 2025, 卷号: 11, 期号: 1, 页码: 14
作者:
Fan, Huancai
;
Lv DY(吕东媛)
;
Lu, Zheng
;
Li HY(李航宇)
;
Qi, Zijuan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/27
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 22
作者:
Liang, Xuewu
;
Huang, Yue
;
Ren, Hairu
;
Liu, Qi
;
Chen, Liang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Ren, Jing
;
Chen, Xin
;
Wang, Hao-yu
;
Yang, Tao
;
Zhang, Kai-rong
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/01
psoriasis
gentiopicroside
keratinocyte
oxidative stress
Keap1-Nrf2 pathway
calcipotriol
Sex differences in plasma lipid profiles, but not in glucose metabolism in patients with first-episode antipsychotics-naive schizophrenia
期刊论文
OAI收割
BRAIN RESEARCH, 2025, 卷号: 1846, 页码: 7
作者:
Li, Shen
;
Liu, Nannan
;
Qi, Dan
;
Niu, Lichao
;
Li, Yanzhe
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2024/11/26
Schizophrenia
First-episode antipsychotics-naive
Glycolipid metabolism
OGTT
Sex differences
A tumor-conditional IL-15 safely synergizes with immunotherapy to enhance antitumor immune responses
期刊论文
OAI收割
MOLECULAR THERAPY, 2024, 卷号: 32, 期号: 12, 页码: 4482-4496
作者:
Shi, Wenqiang
;
Xu, Wei
;
Song, Luyao
;
Zeng, Qiongya
;
Qi, Gen
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/01/14
Therapeutic effect of phycocyanin on chronic obstructive pulmonary disease in mice
期刊论文
OAI收割
JOURNAL OF ADVANCED RESEARCH, 2024, 卷号: 66, 页码: 285-301
作者:
Li, Wenjun
;
Li, Yuanyuan
;
Wang, Qi
;
Liu, Runze
;
Lu, Jianing
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/01/10
Phycocyanin
Chronic obstructive pulmonary disease
Antioxidants
Anti-inflammatory drugs
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor