中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design and structural optimization of novel SOS1 inhibitors in KRAS-driven cancers
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 125, 页码: 8
作者:
Chen, Yating
;
Liu, Qiupei
;
Meng, Xianghui
;
Cao, Wenxu
;
Duo, Lihui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
SOS1 inhibitor
KRAS mutation
SOS1-KRAS interaction
Resistance
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/28
Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Li, Yan-Rong
;
Shangguan, Jinyi
;
Wang, Jian-Min
;
Davies, Ric
;
Santos, Daryl J. D.
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/21
Chemical constituents with immunosuppressive and antitumor activities of Tetradium fraxinifolium (Hook.) TGHartley
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 184, 页码: 6
作者:
Du, En-Lian
;
Tan, Jun-Jie
;
Wang, Yi
;
Jiang, Yu-Xia
;
Chen, Fei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Rutaceae
Tetradium fraxinifolium
Limonoids
Alkaloids
Immunosuppressant
Antitumor
Green synthesis of 2-trifluoromethylquinoline skeletons
via
organocatalytic
N
-[(
α
-trifluoromethyl)vinyl]isatins CN bond activation
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 7, 页码: 10
作者:
Ji, Cong-Bin
;
Xie, Ding-Xiong
;
Chen, Mei
;
Lan, Ye-Ying
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/25
N-[(alpha-Trifluoromethyl)vinyl]isatins
Pfitzinger-type reaction
C-N bond cleavage
2-CF3-quinoline-4-carboxamide
2-CF3-quinoline-4-carboxylicester
Primary Amine-Based Photoclick Chemistry: From Concept to Diverse Applications in Chemical Biology and Medicinal Chemistry
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2025, 卷号: 58, 期号: 13, 页码: 1963-1981
作者:
Hu, Hao
;
Nie, Hui-Jun
;
Chen, Xiao-Hua
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/08/20
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
Risk assessment of CYP3A induction by ginsenoside's metabolites from oral Panax notoginseng (sanqi) extract
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 349, 页码: 11
作者:
Deng, Yang
;
Du, Jing
;
He, Xin
;
Dong, Yan-Xi
;
Wang, Xiao-Lei
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Panax notoginseng
Ginsenoside
Intestinal microbiota
CYP3A induction
Drug interaction
ROS-responsive micelles co-loaded dexamethasone and pristimerin to restore the homeostasis of the inflammatory microenvironment for rheumatoid arthritis therapy
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 6, 页码: 6
作者:
Liang, Ruifeng
;
Tu, Yanbei
;
Hua, Peng
;
Huang, Yongzhuo
;
Chen, Meiwan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/05/27
Rheumatoid arthritis
Micelles
Macrophages
Fibroblast-like synoviocytes
Osteoclastogenesis
Monitoring AGNs with Hβ Asymmetry. V. Long-term Variation and Evolution of the Broad Hβ Emission-line Profiles
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2025, 卷号: 278, 期号: 2
作者:
Fang, Feng-Na
;
Du, Pu
;
Brotherton, Michael S.
;
McLane, Jacob N.
;
Zastrocky, T. E.
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/06/10