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Chinese Academy of Sciences Institutional Repositories Grid
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Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism
期刊论文
OAI收割
LIVER INTERNATIONAL, 2024, 页码: 17
作者:
Hou, Aijun
;
Xu, Xiaoding
;
Zhang, Yu
;
He, Hongxiu
;
Feng, Yihan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Drosha degradation
lipid metabolism
miRNA biogenesis
NAFLD
PRMT5
Diachronous slab-driven Early Cretaceous crustal extension and pulsed magmatic response in southeastern China: Insight from A-type granite and related rocks
期刊论文
OAI收割
GONDWANA RESEARCH, 2024, 卷号: 126, 页码: 22-39
作者:
Chen, Jing-Yuan
;
Yang, Jin-Hui
;
Zhang, Ji-Heng
;
Sun, Jin-Feng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/12/27
Southeastern China
Subduction
A-type granites
Diachronous extension
Early Cretaceous
ABHD6 drives endocytosis of AMPA receptors to regulate synaptic plasticity and learning flexibility
期刊论文
OAI收割
PROGRESS IN NEUROBIOLOGY, 2024, 卷号: 233, 页码: 17
作者:
Wei, Mengping
;
Yang, Lei
;
Su, Feng
;
Liu, Ying
;
Zhao, Xinyi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/25
AMPA receptors
ABHD6
Endocytosis
Synaptic plasticity
Learning flexibility
Comprehensive analysis of phenylpropanoids and butylidenephthalides in
Angelica sinensis
(Oliv.) Diels from different regions and processing methods by high-performance liquid chromatography combined with chemometrics
期刊论文
OAI收割
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2024, 页码: 16
作者:
Sun, Yan
;
Zhou, Jing
;
Hu, Yuxin
;
Chen, Sihan
;
Ni, Hui
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/02/27
Angelicae Sinensis radix
Origin
Chemometrics
Fingerprints
Single standard to determine the multi-components
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:
Feng, Dazhi
;
Liu, Bo
;
Chen, Zhiwei
;
Xu, Jinyi
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/02/27
HPK1 inhibitor
machine learning
virtual screening
free energy perturbation
structural modification
Environmental reconstruction and dating of Shixiakou Locality 1 on China's West Loess Plateau: implications for human adaptive changes apparent during the Last Glacial Maximum (LGM) and post-LGM periods
期刊论文
OAI收割
ARCHAEOLOGICAL AND ANTHROPOLOGICAL SCIENCES, 2024, 卷号: 16, 期号: 1, 页码: 11
作者:
Li, Feng
;
Zhou, Jing
;
Ren, Jincheng
;
Chen, Fuyou
;
Zhou, Xinying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/27
Last Glacial Maximum
Northern China
Western Loess Plateau
Microblade technology
Human adaptation
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:
Wang, Jingyi
;
Lin, Jianbang
;
Chen, Yefei
;
Liu, Jing
;
Zheng, Qiongping
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/01/16
Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model
期刊论文
OAI收割
CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+
作者:
Chen, Yefei
;
Hong, Zexuan
;
Wang, Jingyi
;
Liu, Kunlin
;
Liu, Jing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26