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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
西北高原生物研究所 [9]
水生生物研究所 [9]
上海药物研究所 [7]
自动化研究所 [7]
地理科学与资源研究所 [5]
南京地理与湖泊研究所 [4]
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期刊论文 [58]
会议论文 [4]
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2025 [1]
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Comparative Study on Covalent and Noncovalent Endogenous Albumin-Binding β-Glucuronidase-Activated SN38 Prodrugs for Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8361-8376
作者:
Lu, Yingxin
;
Jiang, Xing
;
Yang, Biyu
;
Ding, Mengyuan
;
Shen, Yanyan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
Enhancing Specific Fluorescence In Situ Hybridization with Quantum Dots for Single-Molecule RNA Imaging in Formalin-Fixed Paraffin-Embedded Tumor Tissues
期刊论文
OAI收割
ACS NANO, 2024, 卷号: 18, 期号: 14, 页码: 9958-9968
作者:
Zhao, Zeyin
;
Jiang, Mengyuan
;
He, Chen
;
Yin, Wenjuan
;
Feng, Yawei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/05/07
single molecule
split-FISH
quantum dots
RNA imaging
quantification
FFPE
clinical samples
diagnostic pathology
Preparation of porous CuS/modified-diatomite composite via a facile
in
situ
loading process for efficient recovery of silver ion from aqueous solution
期刊论文
OAI收割
APPLIED SURFACE SCIENCE, 2024, 卷号: 644, 页码: 11
作者:
Yuan, Weiwei
;
Li, Mengyuan
;
Chen, Haipeng
;
Liu, Guilong
;
Liu, Dong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/09/14
CuS/modified-diatomite
In situ loading
Adsorption
Silver ion
Measurement of cultivated land ecosystem resilience in black soil region of Northeast China under the background of cultivated land protection policy in China: Case study of Qiqihar City
期刊论文
OAI收割
JOURNAL OF CLEANER PRODUCTION, 2024, 卷号: 434, 页码: 14
作者:
Miao, Xinran
;
Li, Zehong
;
Wang, Mengyuan
;
Mei, Jie
;
Chen, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/01
Cultivated land ecosystem
Resilience
Cultivated land protection
Black soil region of Northeast China
Learning Proposal-Aware Re-Ranking for Weakly-Supervised Temporal Action Localization
期刊论文
OAI收割
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS FOR VIDEO TECHNOLOGY, 2024, 卷号: 34, 期号: 1, 页码: 207-220
作者:
Hu, Yufan
;
Fu, Jie
;
Chen, Mengyuan
;
Gao, Junyu
;
Dong, Jianfeng
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/03/26
Proposals
Feature extraction
Location awareness
Videos
Measurement
Task analysis
Optimization
weakly-supervised temporal action localization
Proposal-aware reranking
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Uncertainty-Aware Dual-Evidential Learning for Weakly-Supervised Temporal Action Localization
期刊论文
OAI收割
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2023, 卷号: 45, 期号: 12, 页码: 15896-15911
作者:
Chen, Mengyuan
;
Gao, Junyu
;
Xu, Changsheng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/26
Uncertainty
Background noise
Task analysis
Location awareness
Measurement uncertainty
Interference
Predictive models
Weakly-supervised temporal action localization
evidential deep learning
uncertainty estimation
Vectorized Evidential Learning for Weakly-Supervised Temporal Action Localization
期刊论文
OAI收割
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2023, 卷号: 45, 期号: 12, 页码: 15949-15963
作者:
Gao, Junyu
;
Chen, Mengyuan
;
Xu, Changsheng
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/03/26
Uncertainty
Location awareness
Reliability
Videos
Noise measurement
Estimation
Deep learning
Weakly-supervised learning
temporal action localization
evidential deep learning
uncertainty estimation
Development of HSP90 inhibitors-SN38 conjugates for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11
作者:
Cao, Yuting
;
Shen, Qianqian
;
Ding, Mengyuan
;
Chen, Yi
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2023/10/17
HSP90
SN38 conjugate
Drug accumulation
Cancer treatment
Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Zhu, Mengwei
;
Fu, Tiantian
;
You, Mengyuan
;
Cao, Junyuan
;
Yang, Hanxi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
COVID-19
SARS-CoV-2
3CL protease
Nirmatrelvir
Peptidomimetic inhibitors