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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [49]
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期刊论文 [506]
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Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17
作者:
Jiang, Zhiyang
;
Wang, Na
;
Chen, Jinxiu
;
Xu, Huan
;
Zhu, Wenya
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Trehalose-6-phosphate synthase
Structural optimization
Isopropanolamine compounds
Inhibitors
Fungicide candidates
Proteogenomic characterization of non-functional clinically relevant subgroups
期刊论文
OAI收割
CANCER CELL, 2025, 卷号: 43, 期号: 4, 页码: 36
作者:
Ji, Shunrong
;
Cao, Lihua
;
Gao, Jing
;
Du, Yang
;
Ye, Zeng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy
期刊论文
OAI收割
MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534
作者:
Li, Cuifeng
;
Wei, Shuqi
;
Sun, Donglin
;
Yang, Zhuo
;
Wang, Qi
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Broadband γ-Ray Spectrum of Supernova Remnant Cassiopeia A
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 982, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
Bai, Y. X.
;
Bao, Y. W.
;
Bastieri, D.
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/05
Constraining the Cosmic-Ray Energy Based on Observations of Nearby Galaxy Clusters by LHAASO
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 982, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
Bai, Y. X.
;
Bao, Y. W.
;
Bastieri, D.
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/05
Ligand-binding assays validated for quantitative bioanalysis of a novel antibody-drug conjugate in monkey serum and related application in a nonclinical study
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2025, 卷号: 131, 页码: 11
作者:
Hou, Yingying
;
Miao, Jie
;
Sun, Yajun
;
Shi, Lili
;
Lu, Ouyang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
ADC
LBA
Validation
GLP
PK
Hepatic FXR-FGF4 is required for bile acid homeostasis via an FGFR4-LRH-1 signal node under cholestatic stress
期刊论文
OAI收割
CELL METABOLISM, 2025, 卷号: 37, 期号: 1, 页码: 104-+
作者:
Song, Lintao
;
Hou, Yushu
;
Xu, Da
;
Dai, Xijia
;
Luo, Jianya
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
The influence of steep faults at various avoidance distances on the stability of hard rock caverns: Physical model experiments and DEM simulations
期刊论文
OAI收割
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY, 2024, 卷号: 154, 页码: 16
作者:
Xu, Huai-sheng
;
Li, Shao-jun
;
Xu, Ding-ping
;
Chen, Shi-jie
;
Feng, Guang-liang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/27
Hard rock cavern
Steep fault-cavern distance
Failure mechanism
Physical model experiment
Discrete element method
Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2024, 页码: 3
作者:
Lin, Ze-Min
;
Xiang, Mai
;
Wei, Wen-Hui
;
Fan, Shu-Hui
;
Chen, Li
  |  
收藏
  |  
浏览/下载:237/0
  |  
提交时间:2024/12/11