机构

• 上海药物研究所 [20]
• 中国科学院大学 [2]

采集方式

• OAI收割 [20]
• iSwitch采集 [2]

内容类型

• 期刊论文 [22]

发表日期

• 2023 [1]
• 2022 [2]
• 2021 [1]
• 2020 [4]
• 2019 [1]
• 2018 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Deciphering the functional landscape of phosphosites with deep neural network 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 9, 页码: 23 作者:  Liang, Zhongjie;  Liu, Tonghai;  Li, Qi;  Zhang, Guangyu;  Zhang, Bei   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/12/08 The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 73, 页码: 6 作者:  Wu, Qiqi;  Sun, Zhongya;  Chen, Zhifeng;  Liu, Jingqiu;  Ding, Hong   |  收藏  |  浏览/下载：72/0  |  提交时间：2022/08/30 Glutamate oxaloacetate transaminase 1  Inhibitor  Hydralazine hydrochloride  High -throughput screening   Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis 期刊论文  OAI收割 ADVANCED SCIENCE, 2022, 卷号: 9, 期号: 7, 页码: 2103228 作者:  Mao, Jianhua;  Zhu, Kongkai;  Long, Zhangbiao;  Zhang, Huimin;  Xiao, Bing   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/21 antithrombotic target  bleeding risk  E97A knock-in mice  small molecule  beta 3/Src interaction   Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens   |  收藏  |  浏览/下载：96/0  |  提交时间：2021/08/17 MSpectraAI: a powerful platform for deciphering proteome profiling of multi-tumor mass spectrometry data by using deep neural networks 期刊论文  OAI收割 BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 15 作者:  Wang, Shisheng;  Zhu, Hongwen;  Zhou, Hu;  Cheng, Jingqiu;  Yang, Hao   |  收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24 Raw mass spectrometry data  Proteome profiling  Feature swath extraction  Deep neural networks  Multi-tumor types  Leave-one-out cross prediction strategy   Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion 期刊论文  OAI收割 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310 作者:  Xiao, Bing;  Mao, Jianhua;  Sun, Boyang;  Zhang, Wei;  Wang, Yun   |  收藏  |  浏览/下载：80/0  |  提交时间：2020/07/01 integrins  lipoprotein lipase  lipoproteins  protein kinase D  thrombasthenia   Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5 作者:  Hu, Chujiao;  Zuo, Yu;  Liu, Jingqiu;  Xu, Heng;  Liao, Weike   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 Licochalcone A  Mutant IDH1  Selective inhibitor   A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats 期刊论文  OAI收割 AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10 作者:  Li, Xin;  Wu, Ming;  Chen, Limin;  Lu, Junyan;  Li, Guo   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 FTY720  Sphingosine-1-phosphate  Cordyceps sinensis  Autosomal dominant polycystic kidney disease  Inflammation   Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236 作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian   |  收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01 IDH1 mutation  High-throughput screening  Pan-inhibitor  2-HG  Gliomas   Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298 作者:  Zhu, Kongkai;  Tao, Hongrui;  Song, Jia-Li;  Jin, Lu;  Zhang, Yuanyuan   |  收藏  |  浏览/下载：132/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Arginine methylation  Virtual screening  Molecular docking  Molecular dynamics simulation