中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, Synthesis, and Pharmacological Evaluation of Spiro[carbazole-3,3′-pyrrolidine] Derivatives as cGAS Inhibitors for Treatment of Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 24
作者:
Chen, Mingjie
;
Lei, Shuyue
;
Zhou, Zihua
;
Wang, Meng
;
Feng, Chunlan
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收藏
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浏览/下载:0/0
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提交时间:2024/05/22
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20
作者:
Niu, Pengpeng
;
Tao, Yanxin
;
Lin, Guohao
;
Xu, Huiqi
;
Meng, Qingyuan
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浏览/下载:0/0
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提交时间:2024/05/22
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
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收藏
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浏览/下载:7/0
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提交时间:2024/05/07
Source identification of sedimentary organic carbon in coastal wetlands of the western Bohai Sea
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 913, 页码: 12
作者:
Zhang, Juqin
;
Hao, Qian
;
Li, Qiang
;
Zhao, Xiangwei
;
Fu, Xiaoli
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收藏
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浏览/下载:0/0
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提交时间:2024/05/07
Organic carbon
Sediment source
N-alkanes
Stable carbon isotope
Bohai Sea
Paleogene integrative stratigraphy, biotas and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding regions
期刊论文
OAI收割
SCIENCE CHINA-EARTH SCIENCES, 2024, 页码: 36
作者:
Liu, Jia
;
Song, Ai
;
Ding, Lin
;
Su, Tao
;
Zhou, Zhekun
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收藏
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浏览/下载:18/0
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提交时间:2024/03/14
Qinghai-Tibetan Plateau
Fossils
Biostratigraphy
Paleoenvironment
Paleogeography
Paleogene
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
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收藏
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浏览/下载:7/0
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提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
GeoTPE: A neural network model for geographical topic phrases extraction from literature based on BERT enhanced with relative position embedding
期刊论文
OAI收割
EXPERT SYSTEMS WITH APPLICATIONS, 2024, 卷号: 235, 页码: 14
作者:
Li, Weirong
;
Sun, Kai
;
Zhu, Yunqiang
;
Ding, Fangyu
;
Hu, Lei
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收藏
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浏览/下载:21/0
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提交时间:2023/10/09
GeoTPE
Geographical topic phrases
Geographical literature
BERT
Neural network
Relative position embedding
Target Controllability of Multiplex Networks With Weighted Interlayer Edges
期刊论文
OAI收割
IEEE TRANSACTIONS ON NETWORK SCIENCE AND ENGINEERING, 2024, 卷号: 11, 期号: 1, 页码: 313-325
作者:
Ding, Jie
;
Zhang, Yaozhong
;
Song, Kun
;
Li, Guoqi
;
Wang, Wei
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收藏
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浏览/下载:17/0
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提交时间:2024/03/26
Multiplex networks
weighted networks
target controllability
minimum cost max flow
Occurrence, Distribution, and Trophic Transfer of Pharmaceuticals and Personal Care Products in the Bohai Sea
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023, 卷号: 57, 期号: 51, 页码: 21823-21834
作者:
Guo, Xiaotong
;
Lv, Min
;
Song, Lehui
;
Ding, Jing
;
Man, Mingsan
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收藏
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浏览/下载:9/0
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提交时间:2024/01/26
marine environment
multimedia distribution
influencing factors
bioaccumulation
trophodynamics
health risk assessment
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
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收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably