中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2025 [1]
2023 [6]
2022 [4]
2021 [2]
2020 [1]
2019 [1]
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学科主题
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Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18
作者:
Yang, Ruirui
;
Wang, Bei
;
Su, Zhaoming
;
Song, Ying
;
Zhang, Yingying
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/08/20
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:
Wu, Xinyu
;
Wang, Mingchen
;
Cao, Yu
;
Xu, Ying
;
Yang, Ziqun
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2024/02/27
O-GlcNAcylation
O-GlcNAc transferase
High-throughput screening
Inhibitor
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:
Xu, Zhuo
;
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2023/10/17
Otilonium Bromide
Deubiquitinase
USP28
Selective inhibitor
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24
作者:
Li, Xiao
;
Li, Fei
;
Ye, Fei
;
Guo, Haotian
;
Chen, Wentao
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2023/10/17
Sequence-based drug design as a concept in computational drug design
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:
Chen, Lifan
;
Fan, Zisheng
;
Chang, Jie
;
Yang, Ruirui
;
Hou, Hui
  |  
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2023/10/17
Discovery of new small molecule inhibitors of the BPTF bromodomain
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453
作者:
Liang, Xiaochen
;
Cao, Yu
;
Duan, Zhe
;
Wang, Mingchen
;
Zhang, Naixia
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/27
BPTF bromodomain
BPTF inhibitors
HTRF
c-Myc
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 84, 页码: 117262
作者:
Xie, Yanqiu
;
Fan, Shijie
;
Ni, Dongxuan
;
Wan, Wei
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/03/27
ATG4B inhibitor
DC-ATG4in
Sorafenib
Hepatocellular Carcinoma
Combination therapy
(-)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:
Liu, Tonghai
;
Shi, Wenjia
;
Ding, Yiluan
;
Wu, Qiqi
;
Zhang, Bei
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/12/13
NAD kinase inhibitor
(-)-epigallocatechin gallate
hydrogen-deuterium exchange mass spectrometry
KRAS
Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1
期刊论文
OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 5, 页码: 21
作者:
Zhu, Mengying
;
Wang, Hui
;
Ding, Yiluan
;
Yang, Yuanyuan
;
Xu, Zhuo
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
COH29
cyclin D1
deubiquitinase
inhibitor
USP2
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14
作者:
Xiao, Senhao
;
Guo, Siqi
;
Han, Jie
;
Sun, Yanli
;
Wang, Mingchen
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2022/06/15