中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共17条,第1-10条 帮助

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Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors 期刊论文  OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18
作者:  
Yang, Ruirui;  Wang, Bei;  Su, Zhaoming;  Song, Ying;  Zhang, Yingying
  |  收藏  |  浏览/下载:16/0  |  提交时间:2025/08/20
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:  
Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun
  |  收藏  |  浏览/下载:44/0  |  提交时间:2024/02/27
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:  
Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying
  |  收藏  |  浏览/下载:63/0  |  提交时间:2023/10/17
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24
作者:  
Li, Xiao;  Li, Fei;  Ye, Fei;  Guo, Haotian;  Chen, Wentao
  |  收藏  |  浏览/下载:56/0  |  提交时间:2023/10/17
Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:  
Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui
  |  收藏  |  浏览/下载:91/0  |  提交时间:2023/10/17
Discovery of new small molecule inhibitors of the BPTF bromodomain 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453
作者:  
Liang, Xiaochen;  Cao, Yu;  Duan, Zhe;  Wang, Mingchen;  Zhang, Naixia
  |  收藏  |  浏览/下载:32/0  |  提交时间:2024/03/27
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 84, 页码: 117262
作者:  
Xie, Yanqiu;  Fan, Shijie;  Ni, Dongxuan;  Wan, Wei;  Xu, Pan
  |  收藏  |  浏览/下载:43/0  |  提交时间:2024/03/27
(-)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:  
Liu, Tonghai;  Shi, Wenjia;  Ding, Yiluan;  Wu, Qiqi;  Zhang, Bei
  |  收藏  |  浏览/下载:56/0  |  提交时间:2022/12/13
Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1 期刊论文  OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 5, 页码: 21
作者:  
Zhu, Mengying;  Wang, Hui;  Ding, Yiluan;  Yang, Yuanyuan;  Xu, Zhuo
  |  收藏  |  浏览/下载:46/0  |  提交时间:2022/06/15
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文  OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14
作者:  
Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen
  |  收藏  |  浏览/下载:67/0  |  提交时间:2022/06/15