机构

• 上海药物研究所 [11]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [12]

内容类型

• 期刊论文 [11]
• 学位论文 [1]

发表日期

• 2023 [2]
• 2022 [1]
• 2021 [1]
• 2020 [2]
• 2019 [2]
• 2018 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共12条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12 作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/02/27 O-GlcNAcylation  O-GlcNAc transferase  High-throughput screening  Inhibitor   Discovery of new small molecule inhibitors of the BPTF bromodomain 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453 作者:  Liang, Xiaochen;  Cao, Yu;  Duan, Zhe;  Wang, Mingchen;  Zhang, Naixia   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 BPTF bromodomain  BPTF inhibitors  HTRF  c-Myc   The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490 作者:  Zhang, Shaoqing;  Chen, Yue;  Xu, Zhongli;  Yang, Jun;  Sun, Renhong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/04/10 Hedgehog  Bcl-xL  PROTAC  drug resistance  bone growth   Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702 作者:  Song, Zilan;  Liu, Bo;  Peng, Xia;  Gu, Wangting;  Sun, Yiming   |  收藏  |  浏览/下载：14/0  |  提交时间：2022/06/15 岩藻糖化糖胺聚糖的寡糖结构及其抗乙酰肝素酶活性研究 学位论文  OAI收割 2020 作者:  周路坦   |  收藏  |  浏览/下载：1/0  |  提交时间：2023/11/02 Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer 期刊论文  OAI收割 PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11 作者:  Wang Yuwei;  Tang Chunping;  Yao Sheng;  Lai Huanling;  Li Runze   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 Non-small cell lung cancer  Natural product  Croton tiglium  Protein kinase C  Molecular modelling   Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500 作者:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Lysine acetylation  Bromodomain  Virtual screening  BPTF inhibitor   Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632 作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min   |  收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 non-alcoholic fatty liver disease  AMP-activated protein kinase  AMPK activator  homogeneous time-resolved fluorescence  metabolic disorders  ob/ob mice   Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis 期刊论文  OAI收割 CANCER LETTERS, 2018, 卷号: 431, 页码: 150-160 作者:  Zhang, Xiong;  Zheng, Xingling;  Yang, Hong;  Yan, Juan;  Fu, Xuhong   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 MLL leukemia  Piribedil  H3K4 methylation  Cell cycle  Apoptosis