机构

• 上海药物研究所 [16]
• 中国科学院大学 [1]

采集方式

• OAI收割 [16]
• iSwitch采集 [1]

内容类型

• 期刊论文 [17]

发表日期

• 2024 [2]
• 2023 [2]
• 2022 [3]
• 2021 [3]
• 2020 [1]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共17条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 14, 页码: 12184-12204 作者:  Zhou, Zhenfei;  Huang, Siqi;  Fan, Shijie;  Li, Xueyuan;  Wang, Chengyu   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/08/22 Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4804-4818 作者:  Suo, Yuying;  Du, Daohai;  Chen, Chao;  Zhu, Hongwen;  Wang, Xiongjun   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/07 A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942 作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/27 Small GTPases  Crystal structures of RhoA  Dynamics of switch II  Molecular dynamics simulations  Allosteric pocket   Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 650, 页码: 117-122 作者:  Ni, Yicheng;  Luo, Zhongyuan;  Lv, Yixin;  Ma, Shuyuan;  Luo, Cheng   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 Thioredoxin reductase 1 inhibitor  Chemical probe  High -throughput screening  Thimerosal   (-)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8 作者:  Liu, Tonghai;  Shi, Wenjia;  Ding, Yiluan;  Wu, Qiqi;  Zhang, Bei   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/12/13 NAD kinase inhibitor  (-)-epigallocatechin gallate  hydrogen-deuterium exchange mass spectrometry  KRAS   The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 73, 页码: 6 作者:  Wu, Qiqi;  Sun, Zhongya;  Chen, Zhifeng;  Liu, Jingqiu;  Ding, Hong   |  收藏  |  浏览/下载：72/0  |  提交时间：2022/08/30 Glutamate oxaloacetate transaminase 1  Inhibitor  Hydralazine hydrochloride  High -throughput screening   Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1) 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2174-2190 作者:  Liu, Liping;  Zhu, Rui;  Li, Jiacheng;  Pei, Yuan;  Wang, Shuangshuang   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 Structural basis of ketamine action on human NMDA receptors 期刊论文  OAI收割 NATURE, 2021, 卷号: 596, 期号: 7871, 页码: 301-+ 作者:  Zhang, Youyi;  Ye, Fei;  Zhang, Tongtong;  Lv, Shiyun;  Zhou, Liping   |  收藏  |  浏览/下载：39/0  |  提交时间：2021/11/04 Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens   |  收藏  |  浏览/下载：96/0  |  提交时间：2021/08/17 Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 40, 页码: 127905 作者:  Luo, Zhongyuan;  Du, Daohai;  Liu, Yanjun;  Lu, Tian;  Liu, Liping   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/21 Glucose-6-phosphate dehydrogenase inhibitor  High-throughput screening  Enzyme kinetics assay  Absorption photometry assay