中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [101]
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Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 14
作者:
Liu, Zhihao
;
Lin, Min
;
Liu, Chenyu
;
Chen, Xin
;
Chen, Qian
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
AT 2023lli: A Tidal Disruption Event with Prominent Optical Early Bump and Delayed Episodic X-Ray Emission
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 964, 期号: 2
作者:
Huang, Shifeng
;
Jiang, Ning
;
Zhu, Jiazheng
;
Wang, Yibo
;
Wang, Tinggui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/08
Measurements of All-Particle Energy Spectrum and Mean Logarithmic Mass of Cosmic Rays from 0.3 to 30 PeV with LHAASO-KM2A
期刊论文
OAI收割
Physical Review Letters, 2024, 卷号: 132, 期号: 13
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/04/08
Research Areas
Cosmic ray composition & spectra
Gravitation, Cosmology & Astrophysics
WeldNet: A deep learning based method for weld seam type identification and initial
期刊论文
OAI收割
EXPERT SYSTEMS WITH APPLICATIONS, 2024, 卷号: 238, 页码: 15
作者:
Ma, Yunkai
;
Fan, Junfeng
;
Zhou, Zhen
;
Zhao, Sihan
;
Jing, Fengshui
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/12/21
Weld seam type identification
Initial point guidance
Deep learning
Robot welding
Vision sensors
The First LHAASO Catalog of Gamma-Ray Sources
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2024, 卷号: 271, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
An, Q.
;
Axikegu
;
Bai, Y. X.
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/01
An ultrahigh-energy y-ray bubble powered by a super PeVatron
期刊论文
OAI收割
SCIENCE BULLETIN, 2024, 卷号: 69, 期号: 4, 页码: 449-457
作者:
Cao, Z.
;
Aharonian, F.
;
An, Q.
;
Axikegu
;
Bai, Y. X.
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/01
Cosmic rays
y-rays
Interstellar medium
Star cluster
Estimation of Regional Evapotranspiration Based on the Decouple Model and Remote Sensing Information --a Case Study in Beijing City and Nearby Region
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF REMOTE SENSING, 2024, 页码: 22
作者:
Di, Su-Chuang
;
Li, Zhao-Liang
;
Ren, Yanmin
;
Liu, Meng
;
Jiang, Ya-Zhen
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/04/01
Evapotranspiration (ET)
decouple model
surface resistance
water consumption
Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
Eleven highly oxygenated and anti-inflammatory guaian-8,12-olides from Hedyosmum orientale
期刊论文
OAI收割
TETRAHEDRON, 2024, 卷号: 152, 页码: 8
作者:
Fan, Yao-Yue
;
Zhang, Xin-Ru
;
Zheng, Cheng-Yu
;
Li, Ying
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/25
Hedyosmum orientale
Natural products
Guaian-8,12-olide
Structure elucidation
Anti-inflammatory activity