中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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紫金山天文台 [76]
近代物理研究所 [28]
上海药物研究所 [26]
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期刊论文 [424]
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Advancing active compound discovery for novel drug targets: insights from AI-driven approaches
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12
作者:
Wang, Xing-you
;
Chen, Yang
;
Li, Yu-fan
;
Wei, Chao-yang
;
Liu, Meng-ya
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
AI-driven drug discovery
novel drug targets
molecular design
ligand exploration
phenotypic drug discovery
undruggable targets
Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2025, 卷号: 297, 页码: 12
作者:
Wang, Shen-Tong
;
Yang, Qi
;
Liu, Ming-Kun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/11
Front-loading
Ion channel
Ocean and coastal acidification
Oyster
Resilience
Translational control
GATA1-mediated Notch signaling augment antitumor immunity of CD11b+CD27-natural killer cells maturation via BCL9/β-catenin signal
期刊论文
OAI收割
CELL REPORTS, 2025, 卷号: 44, 期号: 5, 页码: 23
作者:
Yang, Fan
;
Li, Anqi
;
Zhu, Yuanyuan
;
Zhou, Yan
;
Tian, Enming
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2025/04/01
GRB 240529A: A Tale of Two Shocks
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/12/02
Decadal variations in near-surface wind speed across the Northern Hemisphere on a centennial timescale and their possible causes
期刊论文
OAI收割
ADVANCES IN CLIMATE CHANGE RESEARCH, 2024, 卷号: 15, 期号: 6, 页码: 1003-1012
作者:
Li, Lin-Wei
;
Zha, Jin-Lin
;
Chuan, Ting
;
Wu, Jian
;
Zhao, De-Ming
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/03/18
Near-surface wind speed
Centennial timescale
Information flow
Regional difference
Northern Hemisphere
Global marine microbial diversity and its potential in bioprospecting
期刊论文
OAI收割
NATURE, 2024, 页码: 27
作者:
Chen, Jianwei
;
Jia, Yangyang
;
Sun, Ying
;
Liu, Kun
;
Zhou, Changhao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/10/21
Precipitation of Ag-Pb-Zn ores of the Poshan vein deposit in the Qinling orogen (central China) by dilution of magmatic hydrothermal fluids
期刊论文
OAI收割
GEOLOGICAL SOCIETY OF AMERICA BULLETIN, 2024, 卷号: 136, 期号: 9-10, 页码: 4072-4090
作者:
Chai, Ming-Chun
;
Li, Jian-Wei
;
Xia, Xiao-Ping
;
Fan, Gao-Hua
;
Fu, Wei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/01
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function