机构

• 上海药物研究所 [10]

采集方式

• OAI收割 [10]

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浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ginkgetin Alleviates Inflammation and Senescence by Targeting STING 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 15 作者:  Liu, Yadan;  Ye, Jialin;  Fan, Zisheng;  Wu, Xiaolong;  Zhang, Yinghui   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/12/16 cGAS-STING signaling  Ginkgetin  senescence  STING inhibitor  target identification   Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2024, 页码: 14 作者:  Zhang, Yinghui;  Liu, Yadan;  Jiang, Bing;  Chen, Lifan;  Hu, Jie   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/10/21 cGAS-STING signaling  STING inhibitor  TransformerCPI model  Licochalcone D  inflammatory diseases   Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279 作者:  Zhou, Chenmao;  Hao, Xinyue;  Chen, Zhengyang;  Zhang, Runze;  Zhou, Qian   |  收藏  |  浏览/下载：41/0  |  提交时间：2024/03/13 Speckle-type POZ protein (SPOP)  SPOP inhibitors  Clear cell renal cell carcinoma (ccRCC)  Structure-activityrelationship (SAR)   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：26/0  |  提交时间：2024/02/27 Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21 作者:  Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui   |  收藏  |  浏览/下载：50/0  |  提交时间：2023/10/17 Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214 作者:  Zhou, Zehui;  Zhou, Guizhen;  Zhou, Chuan;  Fan, Zisheng;  Cui, Rongrong   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/03/27 Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2619-2622 作者:  Chang, Jie;  Yang, Ruirui;  Chen, Lifan;  Fan, Zisheng;  Zhou, Jingyi   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/08/16 ADP-ribosylation factor 1  Breast cancer  Demethylzeylasteral  Virtual screening   Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942 作者:  Zhou, Chuan;  Fan, Zisheng;  Zhou, Zehui;  Li, Yupeng;  Cui, Rongrong   |  收藏  |  浏览/下载：58/0  |  提交时间：2022/06/15 Active Learning for Drug Design: A Case Study on the Plasma Exposure of Orally Administered Drugs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16838-16853 作者:  Ding, Xiaoyu;  Cui, Rongrong;  Yu, Jie;  Liu, Tiantian;  Zhu, Tingfei   |  收藏  |  浏览/下载：49/0  |  提交时间：2022/06/15 Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文  OAI收割 PROTEIN & CELL, 2021, 页码: 21 作者:  Zhong, Feisheng;  Wu, Xiaolong;  Yang, Ruirui;  Li, Xutong;  Wang, Dingyan   |  收藏  |  浏览/下载：36/0  |  提交时间：2021/12/01 drug target inference  transcriptomics  deep learning  experimental verification