中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [10]
遥感与数字地球研究所 [2]
合肥物质科学研究院 [1]
烟台海岸带研究所 [1]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2025 [1]
2024 [2]
2023 [3]
2022 [2]
2021 [2]
2019 [1]
更多
学科主题
筛选
浏览/检索结果:
共14条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Discovery of 2(1
H
)-Quinoxalinone Derivatives as Potent and Selective MAT2A Inhibitors for the Treatment of MTAP-Deficient Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 2, 页码: 1222-1244
作者:
Li, Chunzheng
;
Lan, Xiaojing
;
Li, Xinge
;
Fu, Yixian
;
Gui, Gang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 12, 页码: 1963-1977
作者:
Gai, Xiameng
;
Liu, Yingluo
;
Lan, Xiaojing
;
Chen, Luoyi
;
Yuan, Tao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/08/20
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703
作者:
Fu, Yixian
;
Huang, Yahui
;
Zhou, Chenchen
;
Li, Xinge
;
Dong, Guoqiang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/01/26
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Jiang, Xifei
;
Deng, Wenjia
;
Tao, Siyao
;
Tang, Zheng
;
Chen, Yuehong
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 6, 页码: 2859-2868
作者:
Wu, Ying
;
Pu, Congying
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
NAMPT
Non-enzymatic function
eNAMPT
Cancer
MDSC
PROTAC
Tumor immunity
Immunotherapy
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2022/06/15
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:318/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole