中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [25]
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Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Targeting NMDA Receptors in Emotional Disorders: Their Role in Neuroprotection
期刊论文
OAI收割
BRAIN SCIENCES, 2022, 卷号: 12, 期号: 10, 页码: 17
作者:
Wang, Siqi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/11/27
NMDAR
depression
anxiety
neuroprotection
PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 10, 页码: 15
作者:
Yu, Xiaolu
;
Long, Yiru
;
Chen, Binfan
;
Tong, Yongliang
;
Shan, Mengwen
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/12/13
PD-L1
TLR7
nanobody-drug-conjugate
cancer immunotherapy
Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination
期刊论文
OAI收割
NANO TODAY, 2022, 卷号: 44, 页码: 16
作者:
Zhao, Pengfei
;
Qu, Jingkun
;
Wu, Aihua
;
Wang, Shuang
;
Tang, Xueping
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15
Fixed-dose codelivery
Glioma
Energy metabolism
Tumor immune microenvironment
Disulfiram
Shikonin
Immunogenic cell death
Tumor-associated macrophage
L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 6, 页码: 14
作者:
Huang, Jing
;
Wang, Xiaobo
;
Li, Bing
;
Shen, Shiyu
;
Wang, Ruina
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/08/16
Immunotherapy
Immune Evation
T-Lymphocytes
Translational Medical Research
Tislelizumab for Relapsed/Refractory Classical Hodgkin Lymphoma: 3-Year Follow-up and Correlative Biomarker Analysis
期刊论文
OAI收割
CLINICAL CANCER RESEARCH, 2022, 卷号: 28
作者:
Song, Yuqin
;
Gao, Quanli
;
Zhang, Huilai
;
Fan, Lei
;
Zhou, Jianfeng
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/05/05
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
;
Ma, Yuan-di
;
Guo, Xiao-zhen
;
Ye, Yun-fei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
Changes in gluconeogenesis pathways and key genes associated with mass mortality in the clam Meretrix petechialis upon Vibrio infection
期刊论文
OAI收割
AQUACULTURE, 2022, 卷号: 548, 页码: 9
作者:
Yu, Jiajia
;
Wang, Hongxia
;
Liu, Baozhong
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/07/18
Meretrix petechialis
Vibrio
Mass mortality
Gluconeogenesis
Marker
Ionizing radiation downregulates estradiol synthesis via endoplasmic reticulum stress and inhibits the proliferation of estrogen receptor-positive breast cancer cells
期刊论文
OAI收割
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 11, 页码: 10
作者:
Yang, Pengfei
;
Feng, Xiu
;
Li, Jin
;
Zhang, Tianyi
;
Sheng, Chengyan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/13
A glimpse of deep-sea adaptation in chemosynthetic holobionts: Depressurization causes DNA fragmentation and cell death of methanotrophic endosymbionts rather than their deep-sea Bathymodiolinae host
期刊论文
OAI收割
MOLECULAR ECOLOGY, 2021, 卷号: 30, 期号: 10, 页码: 2298-2312
作者:
Chen, Hao
;
Wang, Minxiao
;
Li, Mengna
;
Lian, Chao
;
Zhou, Li
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/06/04
bathymodiolinae mussel
chemosynthetic symbiosis
deep‐
sea adaptation
hydrostatic pressure
methane‐
oxidizing bacteria