机构

• 上海药物研究所 [9]

采集方式

• OAI收割 [9]

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浏览/检索结果: 共9条，第1-9条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Identification of benzo[ b ]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 146, 页码: 15 作者:  Cao, Xin-Yu;  Li, Xinge;  Wang, Feng;  Duan, Yichen;  Wu, Xingmei   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/06/27 Serine synthesis pathway  PHGDH  Stattic  Covalent inhibitor  Antitumor   Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 21 作者:  Gao, Dingding;  Tang, Shuai;  Cen, Yixin;  Yuan, Liang;  Lan, Xiaojing   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10 Discovery of PHGDH inhibitors by virtual screening and preliminary structure-activity relationship study 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 121, 页码: 13 作者:  Zhang, Fu-Mao;  Yuan, Liang;  Shi, Xin-Wei;  Feng, Kai-Rui;  Lan, Xiaojing   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Virtual screening  PHGDH  Structure-activity relationships  Antitumor   Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20 作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie   |  收藏  |  浏览/下载：52/0  |  提交时间：2021/06/11 STAT3 signaling pathway  Benzothiazole  Rational design  Antitumor activity  Molecular docking   Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16 作者:  He, Yulong;  Dou, Huixia;  Gao, Dingding;  Wang, Ting   |  收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01 Dual FABP4/5 inhibitor  Structure-based design  Lipolysis inhibition  Anti-inflammatory effects   Synthesis and biological evaluation of novel larotaxel analogues 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 692-710 作者:  Ren, Sumei;  Wang, Yujie;  Wang, Junfei;  Gao, Dingding;  Zhang, Minmin   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Larotaxel  Toxoids  Structure-activity relationship  Semi-synthesis  Drug-resistant  Cytotoxicity   Optimization of 1H-indazol-3-amine derivatives as potent fibroblast growth factor receptor inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 16, 页码: 3782-3786 作者:  Cui, Jing;  Peng, Xia;  Gao, Dingding;  Dai, Yang;  Ai, Jing   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 FGFR  Inhibitors  Cellular activity  Fluorine   Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2673-2680 作者:  Xiao, Qiang;  Qu, Rong;  Gao, Dingding;  Yan, Qi;  Tong, Linjiang   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 5-(Methylthio)pyrimidine derivatives  Mutant selective inhibitors  Epidermal growth factor inhibitor  NSCLC  Structure-based drug design   Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 241-250 作者:  Cai, Haiyan;  Liu, Qiufeng;  Gao, Dingding;  Wang, Ting;  Chen, Tiantian   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 FABP4  Inhibitor  Diabetes  Virtual screening  Crystal structure