机构

• 上海药物研究所 [7]
• 高能物理研究所 [2]
• 深圳先进技术研究院 [1]
• 沈阳应用生态研究所 [1]

采集方式

• OAI收割 [9]
• iSwitch采集 [2]

内容类型

• 期刊论文 [11]

发表日期

• 2023 [1]
• 2022 [1]
• 2020 [2]
• 2019 [2]
• 2017 [1]
• 2016 [1]
• 更多

学科主题

• Chemistry,... [1]
• Materials ... [1]
• Metallurgy... [1]

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：51/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion 期刊论文  OAI收割 CANCER BIOLOGY & THERAPY, 2022, 页码: 14 作者:  Guo, Ne;  Li, Meng-Zhu;  Wang, Li-Min;  Chen, Hua-Dong;  Song, Shan-Shan   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/15 Combination therapy  PARP1  resistance  CXCL3-ERK1/2 signaling  migration and invasion   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong   |  收藏  |  浏览/下载：104/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 714-727 作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 PARP1 inhibitor  PARP1-DNA binding  PARP1-DNA trapping  poly(ADP-ribose) polymerase activity  cytotoxicity   Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文  OAI收割 CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2 作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Low-Discrepancy Blue Noise Sampling 期刊论文  OAI收割 ACM TRANSACTIONS ON GRAPHICS, 2016 作者:  Abdalla G. M. Ahmed;  Hélène Perrier;  David Coeurjolly;  Victor Ostromoukhov;  Jianwei Guo 收藏  |  浏览/下载：38/0  |  提交时间：2017/01/15 Mutual separation characteristics of neighbouring rare earth elements Nd, Sm, Eu and Gd using stepwise chlorination chemical vapour transport 期刊论文  OAI收割 JOURNAL OF ALLOYS AND COMPOUNDS, 1998, 卷号: 269, 期号: 1-2, 页码: 88-91 作者:  Sun, YH;  Wang, ZC;  Guo, L;  Wang, ZC, NE Univ Technol, Dept Chem, Shenyang 110006, Liaoning, Peoples R China   |  收藏  |  浏览/下载：19/0  |  提交时间：2011/09/23 Rare Earth Separation  Binary Oxide Mixture  Chlorination  Chemical Vapour Transport  Vapour Complex   Search for a z' at the z resonance 期刊论文  iSwitch采集 Physics letters b, 1993, 卷号: 306, 期号: 1-2, 页码: 187-196 作者:  ADRIANI, O;  AGUILARBENITEZ, M;  AHLEN, S;  ALCARAZ, J;  ALOISIO, A 收藏  |  浏览/下载：55/0  |  提交时间：2019/04/23