机构

• 上海药物研究所 [24]

采集方式

• OAI收割 [24]

内容类型

• 期刊论文 [24]

发表日期

• 2024 [2]
• 2023 [3]
• 2022 [6]
• 2021 [3]
• 2020 [5]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共24条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18 作者:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/25 Type 2 Diabetes  TGR5 agonist  Betulinic acid  Gut-restricted  Gallbladder-filling effects  Kinetophores   Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16 作者:  Han, Fanghui;  Zhao, Tingting;  Zhang, Yanglong;  Yun, Ying;  Xu, Yuanyuan   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19 SSTR5 antagonist  Gallbladder emptying  Cholesterol gallstones   Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12 作者:  Song, Zhaoxiang;  Lu, Dan;  Sun, Jun;  Ye, Yangliang;  Fang, Jiahui   |  收藏  |  浏览/下载：31/0  |  提交时间：2024/01/16 GPR35  IBD  Lodoxamide   Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929 作者:  Shen, Donghang;  Li, Xin;  Guo, Shimeng;  Xie, Xin;  Nan, Fajun   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/02/27 Huntingdon's disease  G protein-coupled receptor  GPR52  alpha-methylene-gamma-butyrolactones  antagonist   Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Chen, Lili;  Yun, Ying;  Guo, Shimeng;  Wang, Xiaoyan;  Xiong, Muya   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Structures of adenosine receptor A(2B)R bound to endogenous and synthetic agonists 期刊论文  OAI收割 CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 4 作者:  Cai, Hongmin;  Xu, Youwei;  Guo, Shimeng;  He, Xinheng;  Sun, Jun   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 Molecular recognition of morphine and fentanyl by the human mu-opioid receptor 期刊论文  OAI收割 CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+ 作者:  Zhuang, Youwen;  Wang, Yue;  He, Bingqing;  He, Xinheng;  Zhou, X. Edward   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21 作者:  Zhang, Chenlu;  Liu, Yameng;  Wang, Ying;  Ge, Xie;  Jiao, Tingying   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/11/11 Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119 期刊论文  OAI收割 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2022, 页码: 29 作者:  Xu, Peiyu;  Huang, Sijie;  Guo, Shimeng;  Yun, Ying;  Cheng, Xi   |  收藏  |  浏览/下载：18/0  |  提交时间：2022/09/30 Recent progress in assays for GPCR drug discovery 期刊论文  OAI收割 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, 卷号: 323, 期号: 2, 页码: C583-C594 作者:  Guo, Shimeng;  Zhao, Tingting;  Yun, Ying;  Xie, Xin   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/04/10 biased signaling  GPCR  high -throughput screening assays  humanized mouse model  protein  protein interaction