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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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大连化学物理研究所 [73]
上海药物研究所 [70]
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期刊论文 [347]
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De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Targeting Mesothelin Enhances Personalized Neoantigen Vaccine Induced Antitumor Immune Response in Orthotopic Pancreatic Cancer Mouse Models
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 17
作者:
Cai, Zhixiong
;
Li, Zhenli
;
Zhong, Wenting
;
Lin, Fangzhou
;
Dong, Xiuqing
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/01
apCAFs
immunotherapy
mesothelin
neoantigen vaccine
pancreatic cancer
Solidified lake sediment with industrial waste and construction waste used as barrier cover material: mechanical strength, water resistance performance, and microscopic analysis
期刊论文
OAI收割
ENVIRONMENTAL TECHNOLOGY, 2025, 页码: 17
作者:
Yuan, Jiayue
;
Guo, Lin
;
Chen, Shiyu
;
Liu, Ye
;
Feng, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/06/27
Solidified sediment
Industrial waste residue
Cover system
Permeation characteristic
Microstructure
An unmanned aerial system benchmark object detection dataset for deep learning in outfall surveys
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF DIGITAL EARTH, 2024, 卷号: 17, 期号: 1, 页码: 2390443
作者:
Wu, Chengbin
;
Huang, Yaohuan
;
Yang, Haijun
;
Yao, Ling
;
Liu, Yesen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/09/19
Deep learning
object detection dataset
outfalls
UAS imagery
computer vision
Tumor-specific delivery of clickable inhibitor for PD-L1 degradation and mitigating resistance of radioimmunotherapy
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 46, 页码: 17
作者:
Hou, Bo
;
Ye, Jiayi
;
Huang, Lujia
;
Cheng, Wenhao
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/12/16
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment
Engineering PEG10assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccination
期刊论文
OAI收割
ELIFE, 2024, 卷号: 13, 页码: 22
作者:
Tang, Ruijing
;
Guo, Luobin
;
Wei, Tingyu
;
Chen, Tingting
;
Yang, Huan
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/10/21
PEG10
CpG-ODN
neoantigen
Mouse
Targeting the Labile Iron Pool with Engineered DFO Nanosheets to Inhibit Ferroptosis for Parkinson's Disease Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 23
作者:
Lei, Li
;
Yuan, Jiali
;
Dai, Zhijun
;
Xiang, Song
;
Tu, Qiuxia
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/10/21
antioxidant system
engineered nanoregulator
ferroptosis
labile iron pool
Parkinson's disease
A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 18
作者:
Gao, Jing
;
Jiang, Xingyu
;
Lei, Shumin
;
Cheng, Wenhao
;
Lai, Yi
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/09/26
Discrete element analysis of heat transfer characteristics of concrete pavement under electrical heating for snow melting and deicing
期刊论文
OAI收割
CONSTRUCTION AND BUILDING MATERIALS, 2024, 卷号: 432, 页码: 13
作者:
Yang, Liu
;
Liu, Yiming
;
Chen, Zhi
;
Yang, Zhiyong
;
Pei, Yaoyao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/06/27
Concrete pavement
DEM
Microstructure
Heat transfer
Snow melting and deicing