中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
力学研究所 [1]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2023 [1]
2022 [1]
2017 [2]
2014 [1]
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YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 20
作者:
Sun, Yuting
;
Yang, Hui
;
Yuan, Jiaqi
;
Wang, Limin
;
Song, Shanshan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17
Distinct point defect behaviours in body-centered cubic medium-entropy alloy NbZrTi induced by severe lattice distortion
期刊论文
OAI收割
ACTA MATERIALIA, 2022, 卷号: 229, 页码: 14
作者:
Shi, Tan
;
Su, Zhengxiong
;
Li, Jing
;
Liu, Chenguang
;
Yang, Jinxue
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/07/18
Medium-entropy alloys
Point defect properties
First-principles calculations
Ion irradiation
Radiation resistance
Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531
作者:
Chen, Wenhua
;
Guo, Ne
;
Qi, Minghui
;
Dai, Haiying
;
Hong, Minghuang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
Antitumor drug
BRCA1/2
PARP inhibitors
Molecular docking
combining53bp1withbrca1asabiomarkertopredictthesensitivityofpolyadpribosepolymeraseparpinhibitors
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 7, 页码: 1036
作者:
Yang Zhongmin
;
Liao Xuemei
;
Chen Yi
;
Shen Yanyan
;
Yang Xinying
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
homologous recombination repair defects
breast cancer
ovarian cancer
TALEN
combined biomarker
simmiparib
olaparib
Synthesis of isoquinolinone-based tricycles as novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 12, 页码: 2669-2673
作者:
Chen, Jianyang
;
Peng, Haixia
;
He, Jinxue
;
Huan, Xiajuan
;
Miao, Zehong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Isoquinolinone-based tricycles
PARP-1 inhibitors
Antitumor