中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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武汉岩土力学研究所 [17]
上海药物研究所 [16]
宁波材料技术与工程研... [2]
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期刊论文 [46]
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PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2025, 页码: 11
作者:
Long, Jing
;
Shao, Ting
;
Wang, Yongmei
;
Chen, Tianzhi
;
Chen, Yuning
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Digital colloid-enhanced Raman spectroscopy for the pharmacokinetic detection of bioorthogonal drugs
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 页码: 11
作者:
Bi, Xinyuan
;
He, Zhicheng
;
Luo, Zhewen
;
Huang, Wensi
;
Diao, Xingxing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/09/26
Radioactive ADME Demonstrates ARV-110's High Druggability Despite Low Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 15
作者:
He, Yifei
;
Zheng, Yuandong
;
Zhu, Chenggu
;
Lei, Peng
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/09/26
Application of Electro-Activated Dissociation Fragmentation Technique to Identifying Glucuronidation and Oxidative Metabolism Sites of Vepdegestrant by Liquid Chromatography-High Resolution Mass Spectrometry
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2024, 卷号: 52, 期号: 7, 页码: 634-643
作者:
He, Yifei
;
Hou, Pengyi
;
Long, Zhimin
;
Zheng, Yuandong
;
Tang, Chongzhuang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/11/26
IDENTIFYING ACCURATE METABOLISM SITES OF VEPDEGESTRANT USING NOVEL ELECTRON-ACTIVATED DISSOCIATION HIGHRESOLUTION MASS SPECTROMETRY
期刊论文
OAI收割
DRUG METABOLISM AND PHARMACOKINETICS, 2024, 卷号: 55, 页码: 1
作者:
He, Yifei
;
Hou, Pengyi
;
Long, Zhimin
;
Zheng, Yuadong
;
Tang, Chongzhuang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/10/21
AN OVERVIEW OF CDE TECHNICAL GUIDELINE FOR NONCLINICAL STUDY OF ADCS: IMPORTANCE AND STRATEGY OF STUDYING RELEASE OF PAYLOAD-CONTAINING COMPONENTS FROM ADC AND THEIR FURTHER METABOLISM
期刊论文
OAI收割
DRUG METABOLISM AND PHARMACOKINETICS, 2024, 卷号: 55, 页码: 1
作者:
Tang, Chongzhuang
;
Li, Zhiqiang
;
He, Yifei
;
Li, Linwei
;
Diao, Xingxing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/10/21
Pharmacokinetics and metabolite identification of 23-hydroxybetulinic acid in rats by using liquid chromatography-mass spectrometry method
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 10
作者:
Xue, Mingzhen
;
Yang, Cheng
;
Huang, Wensi
;
He, Yifei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/05/22
23-hydroxybetulinic acid
Pharmacokinetics
Metabolism
UPLC-MS
LC-MS/MS
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Rao, Danni
;
Yang, Tao
;
Feng, Huixu
;
An, Qi
;
Zhang, Shaofeng
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [
3
H]Catalpol in Rats: the Main Bioactive Component of
Rehmannia glutinosa
for the Treatment of Ischemic Stroke
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2023, 页码: 10
作者:
Ge, Xinyu
;
Zheng, Yuandong
;
He, Yifei
;
Chen, Chong
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/12/08
[H-3]catalpol
Rehmannia glutinosa
mass balance
tissue distribution
metabolism
intestinal flora
ischemic stroke.