机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2017 [1]
• 2016 [4]
• 2014 [2]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 The Second-generation of Highly Potent Hepatitis C Virus (HCV) NS3/4A Protease Inhibitors: Evolutionary Design Based on Tailor-made Amino Acids, Synthesis and Major Features of Bio-activity 期刊论文  OAI收割 CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 30, 页码: 4493-4554 作者:  Wang, Shuni;  Wang, Yibing;  Wang, Jiang;  Sato, Tatsunori;  Izawa, Kunisuke   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Hepatitis C virus (HCV)  pandemic  direct-acting antiviral agents (DAAs)  NS3/4A protease inhibitor  tailor-made amino acids  structure-activity relationship (SAR)  asymmetric synthesis  ring-closing metathesis (RCM)   Tailor-Made alpha-Amino Acids in the Pharmaceutical Industry: Synthetic Approaches to (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic Acid (Vinyl-ACCA) 期刊论文  OAI收割 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 期号: 16, 页码: 2757-2774 作者:  Sato, Tatsunori;  Izawa, Kunisuke;  Luis Acena, Jose;  Liu, Hong;  Soloshonok, Vadim A.   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Asymmetric synthesis  Amino acids  Medicinal chemistry  Drug design  Antiviral agents   Advanced asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by alkylation/cyclization of newly designed axially chiral Ni(II) complex of glycine Schiff base 期刊论文  OAI收割 AMINO ACIDS, 2016, 卷号: 48, 期号: 4, 页码: 973-986 作者:  Kawashima, Aki;  Shu, Shuangjie;  Takeda, Ryosuke;  Kawamura, Akie;  Sato, Tatsunori   |  收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 Anti-viral (HCV) activity  Asymmetric synthesis  Amino acids  Chirality  Schiff bases   Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas 期刊论文  OAI收割 CHEMICAL REVIEWS, 2016, 卷号: 116, 期号: 2, 页码: 422-518 作者:  Zhou, Yu;  Wang, Jiang;  Gu, Zhanni;  Wang, Shuni;  Zhu, Wei   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Small-Molecule Therapeutics for Ebola Virus (EBOV) Disease Treatment 期刊论文  OAI收割 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 期号: 1, 页码: 8-16 作者:  Izawa, Kunisuke;  Luis Acena, Jose;  Wang, Jiang;  Soloshonok, Vadim A.;  Liu, Hong   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Synthetic methods  Medicinal chemistry  Drug design  Antiviral agents   Chemical Dynamic Kinetic Resolution and S/R Interconversion of Unprotected alpha-Amino Acids 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 卷号: 53, 期号: 45, 页码: 12214-12217 作者:  Takeda, Ryosuke;  Kawamura, Akie;  Kawashima, Aki;  Sato, Tatsunori;  Moriwaki, Hiroki   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 amino acids  chirality  diastereoselectivity  kinetic resolution  nickel   Recent advances in the trifluoromethylation methodology and new CF3-containing drugs 期刊论文  OAI收割 JOURNAL OF FLUORINE CHEMISTRY, 2014, 卷号: 167, 页码: 37-54 作者:  Zhu, Wei;  Wang, Jiang;  Wang, Shuni;  Gu, Zhanni;  Luis Acena, Jose   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Trifluoromethylation  Methodology  Fluorine-containing drugs  Pharmaceuticals  Biological activity