中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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近代物理研究所 [56]
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Rapid Discovery of Celastrol Derivatives as Potent and Selective PRDX1 Inhibitors via Microplate-Based Parallel Compound Library and In Situ Screening
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13609-13627
作者:
Chen, Shuang
;
Wang, Zhenyu
;
Gao, Jia
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/08/20
Analysis of ligustrazine covalent cyclodextrin frameworks in bioinformatics and network pharmacology-based acute lung injury treatment
期刊论文
OAI收割
ARABIAN JOURNAL OF CHEMISTRY, 2025, 卷号: 18, 期号: 4, 页码: 12
作者:
Wu, Di
;
Wang, Xiao Le
;
Jia, Yu
;
He, Si Yu
;
Gao, Ya Ting
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/08/20
Acute lung injury
Bioinformatics
Covalent cyclodextrin frameworks
Ligustrazine
Pulmonary drug delivery
USP7 V517F mutation as a mechanism of inhibitor resistance
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 14
作者:
Miao, Yu-Ling
;
Fan, Fengying
;
Cheng, Yong-Jun
;
Jia, Li
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/05/27
Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:
Peng, Chang
;
Jiang, Haowen
;
Jing, Liya
;
Yang, Wenhua
;
Guan, Xiaotong
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2025/04/01
A downscaling framework with WRF-UCM and LES/RANS models for urban microclimate simulation strategy: Validation through both measurement and mechanism model
期刊论文
OAI收割
BUILDING AND ENVIRONMENT, 2025, 卷号: 269, 页码: 13
作者:
Liu, Jiawen
;
Gao, Huan
;
Jia, Ruoyu
;
Wang, Ran
;
Han, Dongrui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2025/03/03
Urban microclimate simulation
One-way downscaling method
WRF-UCM model
ENVI-met
PALM-4U
The two-resistance mechanism (TRM) model
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Age-related decline in CD8
+
tissue resident memory T cells compromises antitumor immunity
期刊论文
OAI收割
NATURE AGING, 2024, 卷号: 4, 期号: 12, 页码: 1828-+
作者:
Pei, Siyu
;
Deng, Xiuyu
;
Yang, Ruirui
;
Wang, Hui
;
Shi, Jian-Hong
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2025/02/28
Reply to: An Initial Upper Palaeolithic attribution is not empirically supported at Shiyu, northern China
期刊论文
OAI收割
NATURE ECOLOGY & EVOLUTION, 2024, 页码: 4
作者:
Yang, Shi-Xia
;
Zhang, Jia-Fu
;
Yue, Jian-Ping
;
Huan, Fa-Xiang
;
Olle, Andreu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/06/11
Photo-induced protonation assisted nano primary battery for highly efficient immobilization of diverse heavy metal ions
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2024, 卷号: 476
作者:
Ge, Hongjian
;
Chen, Chaowen
;
Li, Sijia
;
Guo, Xinyue
;
Zhang, Jing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/11/22
Multi heavy metal ions immobilization
Photo -induced protonation
Enhanced affinity
Fast electrons transfer
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function