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Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Ginsenoside (20)S-APPT induces ferroptosis in hepatocellular carcinoma and cholangiocarcinoma by targeting FSP1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 18
作者:
Liu, Fan-yu
;
Yang, Yuan-jie
;
Wang, Xue-long
;
Hong, Yan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of
Trichilia connaroides
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 25, 页码: 6772-6776
作者:
Xu, Jia-Xin
;
Zhao, Hai-Yang
;
Li, Xiao-Zhou
;
Li, Zhi-Ying
;
Shen, Tao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Gravitational wave astronomy with TianQin
期刊论文
OAI收割
REPORTS ON PROGRESS IN PHYSICS, 2025, 卷号: 88, 期号: 5
作者:
Li, En-Kun
;
Liu, Shuai
;
Torres-Orjuela, Alejandro
;
Chen, Xian
;
Inayoshi, Kohei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/05/26
gravitational wave
astronomy
TianQin
The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 115, 页码: 6
作者:
Peng, Cheng
;
Sheng, Li
;
Xu, Gao-Ya
;
Qi, Xiao-Lei
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/12/25
Antileukemic
Thiazolyl
Urea
Synthesis
SAR
Quantitative Proteomic Study Reveals Amygdalin Alleviates Liver Fibrosis Through Inhibiting mTOR/ PDCD4/JNK Pathway in Hepatic Stellate Cells
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 3735-3749
作者:
Huang, Hui
;
Ru, Su-Jie
;
Chen, Jia-Mei
;
Liu, Wei
;
Fang, Shan-Hua
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/07/25
amygdalin
PDCD4
HSC activation
proteomics
Characterization of regolith-hosted rare earth element deposits using reflectance spectroscopy: Framework towards an efficient and reliable field exploration tool
期刊论文
OAI收割
JOURNAL OF GEOCHEMICAL EXPLORATION, 2024, 卷号: 267, 页码: 19
作者:
Li, Martin Yan Hei
;
Liu, Jiacheng
;
Tan, Wei
;
Zhou, Jia-Xi
;
Zhou, Mei-Fu
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/04/01
Rare earth elements
Regolith-hosted deposits
Reflectance spectroscopy
VNIR-SWIR spectroscopy
Clay minerals
Weathering
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
;
Yu, Cheng-Yin
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Circulating metabolites of
Borneolum syntheticum
(Bingpian) ameliorate atherosclerosis in ApoE
-/-
mice via inhibiting macrophage foam-cell formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 18
作者:
He, Rong-rong
;
Ma, Chuan-rui
;
He, Xin
;
Dong, Yan-xi
;
Li, Hui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/11/26
Borneolum syntheticum
Bingpian
borneol
isoborneol
metabolism
atherosclerosis