机构

• 西北高原生物研究所 [19]
• 上海药物研究所 [16]
• 地理科学与资源研究所 [5]
• 地质与地球物理研究所 [4]
• 心理研究所 [4]
• 上海硅酸盐研究所 [4]
• 更多

采集方式

• OAI收割 [72]
• iSwitch采集 [2]

内容类型

• 期刊论文 [74]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [11]
• 2021 [4]
• 2020 [4]
• 2019 [9]
• 更多

学科主题

• Cell Biolo... [2]
• Biochemist... [1]
• Pharmacolo... [1]
• Plant Scie... [1]
• Research &... [1]
• 半导体材料 [1]
• 更多

筛选

浏览/检索结果: 共74条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759 作者:  Liu, Zhi;  Jiang, Kailong;  Liu, Yan;  Li, Junfei;  Huang, Siqi   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/09/26 Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287 作者:  Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming   |  收藏  |  浏览/下载：44/0  |  提交时间：2024/02/27 Association between triglyceride glucose index and suicide attempts in patients with first-episode drug-naive major depressive disorder 期刊论文  OAI收割 FRONTIERS IN PSYCHIATRY, 2023, 卷号: 14, 页码: 9 作者:  Liu, Junjun;  Zhu, Xiaomin;  Liu, Yang;  Jia, Fengnan;  Yuan, Hsinsung   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/09 triglyceride glucose index  suicide attempts  insulin resistance  major depressive disorder  association   A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma 期刊论文  OAI收割 CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15 作者:  Jiang, Xifei;  Deng, Wenjia;  Tao, Siyao;  Tang, Zheng;  Chen, Yuehong   |  收藏  |  浏览/下载：31/0  |  提交时间：2023/04/10 PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way 期刊论文  OAI收割 JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 10, 页码: 15 作者:  Yu, Xiaolu;  Long, Yiru;  Chen, Binfan   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/12/13 PD-L1  TLR7  nanobody-drug-conjugate  cancer immunotherapy   Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China 期刊论文  OAI收割 THORACIC CANCER, 2022 作者:  Xu, Chunwei;  Si, Lu;  Wang, Wenxian;  Li, Ziming;  Song, Zhengbo   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/12/22 fusion  precision medicine  solid tumor  targeted therapy  tyrosine receptor kinase   Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8 作者:  Li, Linjie;  Su, Mingbo;  Lu, Weiwei;  Song, Hongzhi;  Liu, Jiaxiang   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/09/30 DNA encoded library  covalent library  library design  covalent inhibitors   Discovery of a Potent and Selective Degrader for USP7 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 卷号: 61, 期号: 33, 页码: e202204395 作者:  Pei, Yuan;  Fu, Jingfeng;  Shi, Yunkai;  Zhang, Mengmeng;  Luo, Guanghao   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/03/21 Apoptotic Pathway  Mutant p53  p53 Mutant Cancer Cells  PROTAC  USP7 Degrader   Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Selection of internal reference gene for normalization of reverse transcription-quantitative polymerase chain reaction analysis in Mycoplasma hyopneumoniae 期刊论文  OAI收割 FRONTIERS IN VETERINARY SCIENCE, 2022, 卷号: 9, 页码: 11 作者:  Li, Shiyang;  Zhou, Yanqing;  Yuan, Ting;  Feng, Zhixin   |  收藏  |  浏览/下载：69/0  |  提交时间：2022/08/30 Mycoplasma hyopneumoniae  RT-qPCR  real-time quantitative polymerase chain reaction  internal reference genes  gatB  virulence