中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [33]
上海硅酸盐研究所 [33]
地理科学与资源研究... [16]
合肥物质科学研究院 [6]
长春光学精密机械与物... [4]
化学研究所 [4]
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期刊论文 [134]
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2025 [4]
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2020 [11]
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Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528
作者:
Guo, Yu
;
Song, Yi
;
Wang, Hanlin
;
Lu, Yang
;
Zhang, Jingyu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2026/01/29
Degrader-antibody conjugate
Antibody-drug conjugate
Cereblon E3 ligase modulator
Immunomodulatory drug
Molecular glue
Targeted protein degradation
Multiple myeloma
Hematologic malignancy
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
GLS1-RNA Polymerase II Axis Mediates Glutamine-Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High-Protein Diets
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 16
作者:
Wu, Wenbiao
;
Jiang, Haowen
;
Liu, Yichang
;
Peng, Chang
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/12/04
alcoholic fatty liver disease
GLS1
hepatic lipogenesis
high-protein diets
RNA polymerase II
A polysaccharide from
Gynostemma
pentaphyllum:
structure characterization and anti-insulin resistance potential through Galectin-3 modulation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 310, 页码: 8
作者:
Ren, Mingwang
;
Sun, Guoqing
;
Ding, Xiaoyu
;
Yu, Xiaolin
;
He, Li
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/07/25
Gynostemma pentaphyllum
Polysaccharides
Structural characterization
Insulin resistance
Galectin-3
Optimization and Biological Evaluation of Novel 1
H
-Pyrrolo[2,3-
c
]pyridin Derivatives as Potent and Reversible Lysine Specific Demethylase 1 Inhibitors for the Treatment of Acute Myelogenous Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 24, 页码: 22080-22103
作者:
Jiang, Hong
;
Li, Cong
;
Li, Na
;
Sheng, Li
;
Wang, Jingkai
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2025/01/14
High carriage and possible hidden spread of multidrug-resistant
Salmonella
among asymptomatic workers in Yulin, China
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 11
作者:
Lu, Xin
;
Luo, Ming
;
Wang, Mengyu
;
Zhou, Zhemin
;
Xu, Jialiang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2025/03/03
A Family of V-Based Null Matrix Alloys with Atomic and Mesoscopic Homogeneity
期刊论文
OAI收割
ACS Applied Engineering Materials, 2024, 卷号: 2, 期号: 10, 页码: 2468-2477
作者:
He, Man
;
Wang, Chen
;
Yang, Hua
;
Wu, Dong-Ying
;
Lee, Jey-Jau
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2026/03/18
Integrated rocksalt-polyanion cathodes with excess lithium and stabilized cycling
期刊论文
OAI收割
NATURE ENERGY, 2024, 卷号: 9, 期号: 12, 页码: 1497-1505
作者:
Huang, YM
;
Dong, YH
;
Yang, Y
;
Liu, TC
;
Yoon, M
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2026/03/18
Chemical approaches for the stereocontrolled synthesis of 1,2-cis-β-D-rhamnosides
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 12, 页码: 886-901
作者:
Cai, Juntao
;
Yuan, Xin
;
Kong, Yuanfang
;
Hu, Yulong
;
Li, Jieming
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2024/02/27
Carbohydrate
Glycosylation
1,2-cis-Glycoside
Stereoselectivity
Total synthesis
/I-Rhamnoside
Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 4, 页码: 1857-1873
作者:
Dong, Ying
;
Hu, Hao
;
Zhang, Xuan
;
Zhang, Yunkai
;
Sun, Xin
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2024/03/27