机构

• 上海药物研究所 [16]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2024 [2]
• 2023 [2]
• 2022 [4]
• 2021 [3]
• 2020 [3]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17 作者:  Zhang, Tao;  Pan, Zilu;  Gao, Jing;  Wu, Qingqing;  Bai, Gang   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/10/21 A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy 期刊论文  OAI收割 CANCER COMMUNICATIONS, 2024, 页码: 5 作者:  Liu, Yingqiang;  Tong, Linjiang;  Zhang, Mengge;  Zhang, Qi;  Liu, Qiupei   |  收藏  |  浏览/下载：37/0  |  提交时间：2024/03/13 Design, synthesis and biological evaluation of KRASG12C-PROTACs 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14 作者:  Zhang, Xiaoyi;  Zhao, Tong;  Sun, Minghao;  Li, Pei;  Lai, Mengzhen   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/04/10 KRASG12C  PROTAC  Covalent inhibitors  Structure-activity relationships (SARs)  Anticancer   Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：120/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor   ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9 作者:  Song, Peiran;  Bai, Gang;  Chan, Shingpan;  Zhang, Tao;  Tong, Linjiang   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/04/10 Bruton's tyrosine kinase  interleukin-2-inducible T cell kinase  ASK120067  B-cell lymphoma  T-cell leukemia   Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations br 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858 作者:  Chen, Hao;  Lai, Mengzhen;  Zhang, Tao;  Chen, Yuqing;  Tong, Linjiang   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/08/16 Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858 作者:  Chen, Hao;  Lai, Mengzhen;  Zhang, Tao;  Chen, Yuqing;  Tong, Linjiang   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7 作者:  Li, Shan;  Zhang, Tao;  Zhu, Su-Jie;  Lei, Chong;  Lai, Mengzhen   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Epidermal Growth Factor Receptor (EGFR)  Resistant Mutation  C797S  Antitumor   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文  OAI收割 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang   |  收藏  |  浏览/下载：107/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 Molecular Cancer, 2021, 卷号: 20, 期号: 1 作者:  Zhang,Tao;  Qu,Rong;  Chan,Shingpan;  Lai,Mengzhen;  Tong,Linjiang   |  收藏  |  浏览/下载：68/0  |  提交时间：2021/11/04