中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [31]
上海生物化学与细胞... [19]
合肥物质科学研究院 [13]
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期刊论文 [111]
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2023 [2]
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Oncology [9]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Wu, Feifei
;
Li, Huiyu
;
An, Qi
;
Sun, Yaoliang
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Hematopoietic progenitor kinase 1 (HPK1)
Cancer immunotherapy
Inhibitor
T cell
N-degron-mediated degradation of the proteolytically activated form of PKC-theta kinase attenuates its pro-apoptotic function
期刊论文
OAI收割
CELLULAR SIGNALLING, 2023, 卷号: 110
作者:
Eldeeb, Mohamed A.
;
Zhou, Wenbin
;
Esmaili, Mansoore
;
Elgohary, Alaa M.
;
Wei, Hai
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01
ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 22, 页码: 15374-15390
作者:
Chan, Shingpan
;
Zhang, Yunong
;
Wang, Jie
;
Yu, Qiuchun
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Potential Anti-Tumor Activity of Nardoguaianone L Isolated from Nardostachys jatamansi DC. in SW1990 Cells
期刊论文
OAI收割
Molecules, 2022, 卷号: 21, 期号: 27, 页码: 7490
作者:
Chun-Yan Sang
;
Yi-Dan Zheng
;
Li-Mei Ma
;
Li-Mei Ma
;
Cheng-Bo Wang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/12/07
natural products
Nardostachys jatamansi DC.
pancreatic cancer
iTRAQ/TMT
MET/PTEN/TGF-β pathway
Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors
期刊论文
OAI收割
EMBO REPORTS, 2022, 页码: 17
作者:
Jiang, Zhiwu
;
Cheng, Lin
;
Wu, Zhiping
;
Zhou, Linfu
;
Wang, Haitao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
biomarkers
hepatocellular carcinoma
humanized mouse models
immunotherapy
oncogenes
Effect of donor characteristics on T cell-replete haploidentical stem cell transplantation over the last 10 years at a single institution
期刊论文
OAI收割
BRITISH JOURNAL OF HAEMATOLOGY, 2021
作者:
Wu, Yibo
;
Lai, Xiaoyu
;
Shi, Jimin
;
Tan, Yamin
;
Zhao, Yanmin
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/10
haploidentical
haematopoietic stem cell transplantation
donor selection
donor characteristics
donor age
female to male
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/12/16