中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [94]
西北高原生物研究所 [12]
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期刊论文 [155]
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生命有机化学 [2]
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A natural small molecule isoginkgetin alleviates hypercholesterolemia and atherosclerosis by targeting ACLY
期刊论文
OAI收割
THERANOSTICS, 2025, 卷号: 15, 期号: 10, 页码: 4325-4344
作者:
Zhang, Zhidan
;
Chen, Meijie
;
Xu, Yitong
;
Wang, Zhihua
;
Liu, Zhenghong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/06/23
Atherosclerosis
Hyperlipidemia
ATP-Citrate lyase (ACLY)
lipid metabolism
Isoginkgetin
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794
作者:
Liu, Yun
;
Yu, Chengyin
;
Zhang, Yifan
;
Xie, Zhifu
;
Wang, Yating
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/24
safety
tolerability
pharmacokinetics
pharmacodynamics
BGT-002
novel ACLY inhibitor
Investigating the formation and evolution of plant diversity patterns in the Qiangtang Plateau based on phylofloristics approach
期刊论文
OAI收割
GLOBAL ECOLOGY AND CONSERVATION, 2025, 卷号: 58
作者:
Li, Xiaoping
;
Han, Yun
;
Miao, Lei
;
Xu, Hao
;
Yu, Jingya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/11/27
Qiangtang Plateau
Seed plants
Phylofloristics
Plastid genome
Divergence time
Plant diversity modulates hierarchical responses of carbon cycle processes to warming and grazing in an alpine meadow
期刊论文
OAI收割
JOURNAL OF PLANT ECOLOGY, 2025, 卷号: 18, 期号: 2
作者:
Lu, Wangwang
;
Sun, Jianping
;
Li, Bowen
;
Zhou, Yang
;
Luo, Caiyun
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/11/27
hierarchical responses of carbon cycles
plant diversity
warming
summer and winter grazing
alpine meadow
Qinghai-Tibetan Plateau
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Genetic structure and conservation implications of Lancea tibetica (Mazaceae), a traditional Tibetan medicinal plant endemic to the Qinghai- Tibet Plateau
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2025, 卷号: 25, 期号: 1
作者:
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/11/27
Lancea tibetica
Allopatric divergence
RAD-seq
Genetic structure
Qinghai-Tibet Plateau
Species distribution modeling
Comparative and phylogenetic analysis of Potentilla and Dasiphora (Rosaceae) based on plastid genome
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2025, 卷号: 25, 期号: 1
作者:
Li, Xiaoping
;
Xu, Hao
;
Yu, Jingya
;
Han, Yun
;
Han, Shuang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/11/27
Potentilla
Dasiphora
Plastid genome
Comparative genomics
Phylogenetic analysis
Cytonuclear discordance
Multiple molecular data provide new insights into phylogeny and historical biogeography of East Asian Artemisia L. (Asteraceae)
期刊论文
OAI收割
BOTANICAL JOURNAL OF THE LINNEAN SOCIETY, 2025, 卷号: 209, 期号: 3, 页码: 250
作者:
Yu, Jingya
;
Han, Yun
;
Xia, Mingze
;
Xu, Hao
;
Han, Shuang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/11/27
Artemisia
phylogeny
plastome
ribosomal DNA
SNP
Trade-off between growing season length and herbaceous growth on the Third Pole
期刊论文
OAI收割
JOURNAL OF PLANT ECOLOGY, 2025, 卷号: 18, 期号: 4
作者:
Meng, Fandong
;
Sun, Jianping
;
Lu, Wangwang
;
Zhang, Zhenhua
;
Li, Bowen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/11/27
leaf economic spectrum
plant functional traits
phenology
common garden
Tibetan Plateau
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489
作者:
Cheng, Tingting
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收藏
  |  
浏览/下载:41/0
  |  
提交时间:2025/02/28
metabolic diseases
ATP-citrate lyase (ACLY)
lipogenesis
ACLY inhibitors
dienyldicarboxylic acid