机构

• 上海药物研究所 [33]
• 化学研究所 [19]
• 地理科学与资源研究... [13]
• 烟台海岸带研究所 [12]
• 西北高原生物研究所 [11]
• 生态环境研究中心 [11]
• 更多

采集方式

• OAI收割 [232]
• iSwitch采集 [11]

内容类型

• 期刊论文 [222]
• 会议论文 [21]

发表日期

• 2025 [8]
• 2024 [15]
• 2023 [20]
• 2022 [34]
• 2021 [26]
• 2020 [20]
• 更多

学科主题

• Cell Biolo... [4]
• Food Scien... [4]
• Biochemist... [2]
• Chemistry,... [2]
• Gastroente... [2]
• Materials ... [2]
• 更多

筛选

浏览/检索结果: 共243条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9 作者:  Li, Linquan;  Gu, Xi;  Meng, Jingyi;  Wen, Yiming;  Yi, Jing   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/05/27 p53 Y220C  Synthesis  Structural modification  Drug design   Numerical investigation on helium pressurization behavior of cryogenic propellant in microgravity 期刊论文  OAI收割 APPLIED THERMAL ENGINEERING, 2025, 卷号: 269 作者:  Guo, Songyuan;  Jiang, Zan;  Li, Jianqiang;  Xu, Pengli;  Zhuan, Rui   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/07/21 Cryogenic propellant  Microgravity  Pressurization  Species transfer   Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2025, 卷号: 20, 期号: 6, 页码: 1319-1332 作者:  Yang, Xinyu;  Li, Yanbei;  Zhou, Jingyi;  Zhou, Yuanyang;  Lin, Kexin   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/07/25 Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885 作者:  Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/07/25 RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer 期刊论文  OAI收割 FRONTIERS IN IMMUNOLOGY, 2025, 卷号: 16, 页码: 12 作者:  Wang, Chen;  Chen, Mengyan;  Chen, Panyu;  Han, Jinlu;  Hu, Hong   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/07/25 colorectal cancer  RBM15  microenvironment  RNA modification  m(6)A   Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer 期刊论文  OAI收割 NATURE CANCER, 2025, 页码: 37 作者:  Wang, Hanling;  Zhang, Sulin;  Pan, Qiang;  Guo, Jiacheng;  Li, Ni   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/05/27 Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 14 作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue   |  收藏  |  浏览/下载：22/0  |  提交时间：2025/04/01 p53 Y220C  Covalent stabilizer  Virtual screening  Molecular dynamics  DNA binding  Structure-activity relationship  Cancer therapy   Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Reproductive and germ-cell mutagenic effects of poly-and perfluoroalkyl substances (PFAS) to Caenorhabditis elegans after multigenerational exposure 期刊论文  OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 954 作者:  Cao, Zhenxiao;  Dai, Linglong;  Li, Jiali;  Zhang, Jingyi;  Wang, Xialian   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/11/20 PFAS  Multigenerational exposure  Caenorhabditis elegans  Germ cell mutagenicity  Whole genome sequencing   Research on the viscoelastic scCO 2 foam systems synergistically stabilized by nonionic/zwitterionic mixed surfactants 期刊论文  OAI收割 COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2024, 卷号: 697, 页码: 14 作者:  Zheng, Nanxin;  Zhu, Jingyi;  Yang, Zhaozhong;  Li, Xiaogang;  Li, Qi   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/06/27 ScCO2 foam fluid  Synergistic effect  Wormlike micelles  Foam stabilization mechanism  Microstructure