中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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海洋研究所 [22]
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Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Solid-state screening and dry powder inhaler development of ziyuglycoside II sodium salt for enhanced bioavailability
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 681, 页码: 11
作者:
Zhang, Hanwen
;
Wang, Siwen
;
Slimani, Sara
;
Lv, Yuting
;
Nie, Qin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Bioavailability
Dry powder inhaler
Saponin
Solid-state screening
Ziyuglycoside II sodium salt
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/05/07
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
A radiomics and genomics-derived model for predicting metastasis and prognosis in colorectal cancer
期刊论文
OAI收割
CARCINOGENESIS, 2024, 页码: 11
作者:
Li, Xue
;
Wu, Meng
;
Wu, Min
;
Liu, Jie
;
Song, Li
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/03/26
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 3
作者:
Yu, Lei
;
Zhao, Pengcheng
;
Sun, Yaoliang
;
Zheng, Zening
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/26
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Wu, Feifei
;
Li, Huiyu
;
An, Qi
;
Sun, Yaoliang
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2023/10/17
Hematopoietic progenitor kinase 1 (HPK1)
Cancer immunotherapy
Inhibitor
T cell
Seismic Azimuthal Anisotropy of Northeastern Tibetan Plateau From Ambient Noise Double Beamforming Tomography: Implications for Crustal Deformation
期刊论文
OAI收割
JOURNAL OF GEOPHYSICAL RESEARCH-SOLID EARTH, 2023, 卷号: 128, 期号: 6, 页码: 16
作者:
Wu, Xiaoyang
;
Guo, Zhen
;
Li, Shilin
;
Yu, Yong
;
Bai, Qipeng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/12/13
seismic ambient noise tomography
double beamforming
northeastern Tibetan Plateau
seismic azimuthal anisotropy
crustal deformation
Multiple pulses of fluids involved in the formation of carbonatite-related REE deposits as revealed by fluorite
期刊论文
OAI收割
Ore Geology Reviews, 2023, 卷号: 159, 页码: 105546
作者:
Shilin Li
;
Wei Zhang
;
Jiali Cai
;
Fangyue Wang
;
Wei Terry Chen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/09