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浏览/检索结果: 共259条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of novel selective PRMT5-MTA inhibitors through structure-based virtual screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2026, 卷号: 168, 页码: 17 作者:  Ma, Ning;  Chen, Yang;  Liang, Yiru;  Chen, Xiaoxu;  Song, Fengnan   |  收藏  |   A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers 期刊论文  OAI收割 CANCER CELL, 2025, 卷号: 43, 期号: 10, 页码: 32 作者:  Feng, Juanjuan;  Xiao, Xuanzheng;  Xia, Xinting;  Min, Jian;  Tang, Weiying   |  收藏  |   Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18 作者:  Yang, Ruirui;  Wang, Bei;  Su, Zhaoming;  Song, Ying;  Zhang, Yingying   |  收藏  |   Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9 作者:  Li, Linquan;  Gu, Xi;  Meng, Jingyi;  Wen, Yiming;  Yi, Jing   |  收藏  |   Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2025, 卷号: 20, 期号: 6, 页码: 1319-1332 作者:  Yang, Xinyu;  Li, Yanbei;  Zhou, Jingyi;  Zhou, Yuanyang;  Lin, Kexin   |  收藏  |   Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885 作者:  Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming   |  收藏  |   Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer 期刊论文  OAI收割 NATURE CANCER, 2025, 页码: 37 作者:  Wang, Hanling;  Zhang, Sulin;  Pan, Qiang;  Guo, Jiacheng;  Li, Ni   |  收藏  |   Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 14 作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue   |  收藏  |   Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |   SurfDock is a surface-informed diffusion generative model for reliable and accurate protein-ligand complex prediction 期刊论文  OAI收割 NATURE METHODS, 2024, 页码: 24 作者:  Cao, Duanhua   |  收藏  |