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浏览/检索结果: 共7759条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   Polycomponent metal-organic frameworks of substituent polydispersion hydroxypropyl-β-cyclodextrin as inhalable drug carrier 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2025, 卷号: 362, 页码: 12 作者:  He, Xiaojian;  Xu, Huipeng;  Zhao, Xiangyu;  Li, Feng;  Peng, Ningning   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/07/25 Metal-organic frameworks  Polycomponent  Hydroxypropyl-beta-cyclodextrin  Polydispersion  Inhalation delivery   EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1 作者:  Jiang, Shuai-Qing;  Xu, Dong;  Hoof, Agnes P. C. van;  Lei, Wei-Hua;  Liu, Yuan   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/07/28 Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong   |  收藏  |  浏览/下载：24/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7 作者:  Cao, Zhen;  Aharonian, F.;  Axikegu;  Bai, Y. X.;  Bao, Y. W.   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/06/10 gamma rays  cosmic rays  supernova remnant  young massive cluster  pulsar   The Overview and Trial Observations of AIMS 期刊论文  OAI收割 RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7 作者:  Deng, Yuanyong;  Wang, Dongguang;  Hua, Jianwen;  Xu, Songbo;  Liang, Ming   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/07/14 Sun: infrared  methods: observational  instrumentation: spectrographs   Advancing active compound discovery for novel drug targets: insights from AI-driven approaches 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12 作者:  Wang, Xing-you;  Chen, Yang;  Li, Yu-fan;  Wei, Chao-yang;  Liu, Meng-ya   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/08/20 AI-driven drug discovery  novel drug targets  molecular design  ligand exploration  phenotypic drug discovery  undruggable targets   Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of Trichilia connaroides 期刊论文  OAI收割 ORGANIC LETTERS, 2025, 卷号: 27, 期号: 25, 页码: 6772-6776 作者:  Xu, Jia-Xin;  Zhao, Hai-Yang;  Li, Xiao-Zhou;  Li, Zhi-Ying;  Shen, Tao   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Three-and-a-half million years of Tibetan Plateau vegetation dynamics in response to climate change 期刊论文  OAI收割 NATURE ECOLOGY & EVOLUTION, 2025, 卷号: N/A 作者:  Zhao, Yan;  Qin, Feng;  Cui, Qiaoyu;  Li, Quan;  Cui, Yifan   |  收藏  |  浏览/下载：11/0  |  提交时间：2025/07/18