中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/ NF-κB/MLCK/MLC signaling in ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 162, 页码: 12
作者:
Zhou, Ruochen
;
Cui, Yuanyuan
;
Wang, Weihao
;
Qu, Yidan
;
Zhang, Gaojie
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Ubiquitin-specific protease 2
Ulcerative colitis
Intestinal epithelial cell
Tight junction
Recent advances in traditional Chinese medicine metabolism: Sample pre-treatment, MS-oriented analytical strategies and typical applications
期刊论文
OAI收割
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2025, 卷号: 189, 页码: 22
作者:
Hong, Li-li
;
Cui, Dian-xin
;
Wang, Hong-da
;
Jing, Qi
;
Li, Xue
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/06/23
Traditional Chinese medicine metabolism
Bio-samples pre-treatment
Mass spectrometry
Data acquisition
Data processing
Application
Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/28
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Impact of spatial transfer of farmland on the food-water-GHG nexus in China during 2000-2020
期刊论文
OAI收割
RESOURCES CONSERVATION AND RECYCLING, 2025, 卷号: 221, 页码: 108390
作者:
Liu, Yunxi
;
Wang, Xue
;
Tan, Minghong
;
Zhang, Fuyao
;
Li, Xiubin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/18
Spatial transfer of farmland
Food-water-GHG
Coupled coordination degree
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
A CMTM6 Nanobody Overcomes EGFR-TKI Resistance in Non-Small Cell Lung Cancer
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 卷号: 12, 期号: 27, 页码: 17
作者:
Xia, Lu
;
Wang, Jichuan
;
Xue, Hui
;
Li, Haimeng
;
Li, Qinghua
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
CMTM6
EGFR
EGFR-TKIs resistance
NSCLC
nanobody
Stable isotope tracing the transformation dynamics of diverse water bodies in the Manas River Basin, Northwest China
期刊论文
OAI收割
APPLIED WATER SCIENCE, 2025, 卷号: 15, 期号: 7, 页码: 156
作者:
Zhang, Heng
;
Tian, Lijun
;
Tian, Hao
;
Farid, Muhammad Arsalan
;
Li, Xiaolong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/07/18
Manas River Basin
Hydrogen and oxygen isotopes
Precipitation
Surface water
Groundwater
MixSIAR model