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浏览/检索结果: 共358条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Enhanced Bioactivity of Natural Products by Halogenation: A Database Survey and Quantum Chemistry Calculation Study 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10486-10496 作者:  Cao, Ruini;  Li, Jintian;  Liao, Qingyi;  Shao, Mei;  Zhang, Qian   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/07/25 Discovery of multi-chitinase inhibitors cinnamyl thiazolidinone compounds as candidates for insect growth regulators via ligand-based optimization strategies 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 306, 页码: 14 作者:  Jiang, Zhiyang;  Shi, Dongmei;  Fu, Haoyu   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/05/27 Multi-chitinase inhibitor  Cinnamaldehyde compounds  Thiazolidinone compounds  Ligand-based optimization  Insect growth regulators (IGRs)   Targeting Two Odorant-Binding Proteins in Acyrthosiphon pisum: Discovery of Novel Jasmone Derivatives as Aphid Repellents 期刊论文  OAI收割 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 卷号: 73, 期号: 19, 页码: 11998-12013 作者:  Zhu, Ziwei;  Li, Huilin;  Zhu, Wenya;  Du, Shaoqing;  Yang, Zhaokai   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/06/23 odorant-binding proteins  jasmone derivatives  rational design  aphid repellents  insect behaviorregulators   Dynamically chiral phosphonic acid-type metallo-β-lactamase inhibitors 期刊论文  OAI收割 COMMUNICATIONS CHEMISTRY, 2025, 卷号: 8, 期号: 1, 页码: 13 作者:  Gulyas, Kinga Virag;  Zhou, Liping   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/06/23 Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy 期刊论文  OAI收割 MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534 作者:  Li, Cuifeng;  Wei, Shuqi;  Sun, Donglin;  Yang, Zhuo;  Wang, Qi   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/05/27 Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11 作者:  Tang, Bixi;  Xie, Like;  Wang, Yangyang;  Shi, Yulong;  Kan, Weijuan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/11/26 Lung first-pass effect  Tanreqing injection  Pharmacokinetics  Sepsis-associated acute lung injury  Acute respiratory distress syndrome   B(MIDA)-directed site-selective intermolecular halofluoroalkylation of alkenes: synthesis of diversely functionalized building blocks 期刊论文  OAI收割 CHEMICAL SCIENCE, 2025, 页码: 8 作者:  Wu, Hengbo;  Luo, Ruitong   |  收藏  |  浏览/下载：28/0  |  提交时间：2025/04/01 F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：26/0  |  提交时间：2025/02/28 Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248 作者:  Wang, Yingying;  Zhang, Youping;  Luo, Hao;  Wei, Wei;  Liu, Wanting   |  收藏  |  浏览/下载：27/0  |  提交时间：2025/04/01 Ubiquitin-specific protease 2  KRAS  Gambogic acid  Multiple myeloma  Degradation  Ubiquitination  Allosteric pocket  Deubiquitination