机构

• 上海药物研究所 [104]
• 新疆理化技术研究所 [11]
• 地理科学与资源研究所 [6]
• 自动化研究所 [6]
• 深圳先进技术研究院 [5]
• 地质与地球物理研究所 [5]
• 更多

采集方式

• OAI收割 [163]
• iSwitch采集 [6]

内容类型

• 期刊论文 [160]
• 会议论文 [9]

发表日期

• 2025 [3]
• 2024 [19]
• 2023 [17]
• 2022 [22]
• 2021 [25]
• 2020 [7]
• 更多

学科主题

• Biochemist... [1]
• Engineerin... [1]
• Geology [1]
• Water Reso... [1]

筛选

浏览/检索结果: 共169条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307 作者:  Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/04/01 Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15 作者:  Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/01 Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20 作者:  Luo, Menglan;  Ye, Yunfei;  Tang, Lu;  Kan, Weijuan;  Chen, Lin   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/11/26 Menin  Covalent inhibitor  Antitumor  Degradation   (2R,6R)-hydroxynorketamine alleviates PTSD-like endophenotypes by regulating the PI3K/AKT signaling pathway in rats 期刊论文  OAI收割 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 245, 页码: 16 作者:  Liu, Lifen;  Li, Rui   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/11/18 Post-traumatic stress disorder  Negative emotions  PI3K/AKT signaling pathway  (2R  6R)-HNK   Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10 作者:  Yu, Qian;  Gao, Lixin;  Xu, Linhao;  Han, Yubing;  Cao, Yu   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/12/11 Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Chen, Beijing;  Sun, Mingyang;  Zhang, Chun;  Huang, Qi;  Teng, Dan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/12/25 Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245 作者:  Saidahmatov, Abdusaid;  Li, Jianan;  Xu, Shihao;  Hu, Xiaobei;  Gao, Xiangqian   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/10/21 Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 8 作者:  Zou, Wanyi;  Li, Mengna;  Wan, Shili;  Ma, Jingkun;  Lian, Linan   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/09/26 acute leukemia  MDM2  oxidative phosphorylation  PRMT3  PROTAC   Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759 作者:  Liu, Zhi;  Jiang, Kailong;  Liu, Yan;  Li, Junfei;  Huang, Siqi   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/09/26