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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共66条，第1-10条 帮助

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Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia 期刊论文  OAI收割
CANCER RESEARCH, 2025, 卷号: 85, 期号: 1, 页码: 101-117
作者:  Luo, Ziwei;  Lin, Chencen;  Yu, Chuwei;  Yuan, Changxian;  Wu, Wenyong
  |  收藏  |  浏览/下载：15/0  |  提交时间：2025/02/28
Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein 期刊论文  OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 9
作者:  Li, Rui;  Chen, Lin;  He, Xinheng;  Cao, Duanhua;  Zhang, Zehong
  |  收藏  |  浏览/下载：23/0  |  提交时间：2023/12/11
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao
  |  收藏  |  浏览/下载：66/0  |  提交时间：2023/10/17
Selective Electrochemical Benzylic C(sp(3))-H Oxidations in Fluoroalcohols 期刊论文  OAI收割
CHEMISTRYSELECT, 2023, 卷号: 8, 期号: 27, 页码: 4
作者:  Shen, Haiwei;  Yang, Bo;  Lin, Jiusheng;  Zheng, Mingyue;  Jiang, Hualiang
  |  收藏  |  浏览/下载：37/0  |  提交时间：2023/10/17
PanGu Drug Model: learn a molecule like a human 期刊论文  OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2022, 页码: 4
作者:  Lin, Xinyuan;  Xu, Chi;  Xiong, Zhaoping;  Zhang, Xinfeng;  Ni, Ningxi
  |  收藏  |  浏览/下载：36/0  |  提交时间：2023/04/10
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192
作者:  Liao, Liping;  Dang, Wenzhen;  Lin, Tingting;  Yu, Jinghua;  Liu, Tonghai
  |  收藏  |  浏览/下载：35/0  |  提交时间：2023/04/10
Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 16, 页码: 11034-11057
作者:  Li, Jiacheng;  Liu, Ting;  Song, Yuanli;  Wang, Mingyu;  Liu, Liping
  |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/21

Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold

 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12
作者:  Lu, Haibo;  Lu, Tian;  Zu, Shijia;  Duan, Zhe;  Guang, Yiman
  |  收藏  |  浏览/下载：43/0  |  提交时间：2022/08/16
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong
  |  收藏  |  浏览/下载：117/0  |  提交时间：2021/12/16
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu
  |  收藏  |  浏览/下载：54/0  |  提交时间：2021/12/01