中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共137条,第1-10条 帮助

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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:  
Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/25
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2 期刊论文  OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:  
Liu, Yaowen;  Nie, Tianqing;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/13
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:  
Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao
  |  收藏  |  浏览/下载:39/0  |  提交时间:2023/10/17
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XXV. Structurally diverse triterpenoids and diterpenoids from two endangered Pinaceae plants endemic to the Chinese Qinling Mountains and their bioactivities 期刊论文  OAI收割
PHYTOCHEMISTRY, 2022, 卷号: 203, 页码: 14
作者:  
Jiang, Wei;  Zhao, Ze-Yu;  Tong, Ying-Peng;  Ma, Guang-Lei;  Zang, Yi
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/09/30
Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:  
Zhang, Chenlu;  Liu, Yameng;  Wang, Ying;  Ge, Xie;  Jiao, Tingying
  |  收藏  |  浏览/下载:34/0  |  提交时间:2022/11/11
Synthesis and Biological Evaluation of C-17-Amino-Substituted Pyrazole-Fused Betulinic Acid Derivatives as Novel Agents for Osteoarthritis Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13676-13692
作者:  
Wang, Jie;  Wei, Wenhui;  Zhang, Xiaofei;  Cao, Shiqi;  Hu, Bintao
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/21
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:  
Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan
  |  收藏  |  浏览/下载:42/0  |  提交时间:2021/11/04
A review on biomass-derived levulinic acid for application in drug synthesis 期刊论文  OAI收割
CRITICAL REVIEWS IN BIOTECHNOLOGY, 2021, 页码: 34
作者:  
Zhang, Mingyue;  Wang, Nan
  |  收藏  |  浏览/下载:33/0  |  提交时间:2021/10/27
Synthesis of a Hexavalent Betulinic Acid Derivative as a Hemagglutinin-Targeted Influenza Virus Entry Inhibitor 期刊论文  OAI收割
MOLECULAR PHARMACEUTICS, 2020
作者:  
Chen, Yingying;  Wang, Xinchen;  Zhu, Yinbiao;  Si, Longlong;  Zhang, Bo
  |  收藏  |  浏览/下载:33/0  |  提交时间:2021/01/05
A New 28-Nor-oleanane Triterpene from Excoecaria agallocha 期刊论文  OAI收割
NATURAL PRODUCT COMMUNICATIONS, 2018, 卷号: 13, 期号: 1, 页码: 21-22
作者:  
Mo, DJ (Mo, De-Juan);  Li, J (Li, Jun)
  |  收藏  |  浏览/下载:24/0  |  提交时间:2018/02/25