中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [138]
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期刊论文 [254]
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浏览/检索结果:
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Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2025, 卷号: 26, 期号: 5, 页码: 46
作者:
Zhu, Qingchen
;
Zhang, Guiheng
;
Cao, Ming
;
Huang, Huan
;
He, Dan
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2025/06/23
Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481
作者:
Wu, Xinyuan
;
Pan, Jiayi
;
Fan, Rufeng
;
Zhang, Yiwei
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer
期刊论文
OAI收割
NATURE CANCER, 2025, 页码: 37
作者:
Wang, Hanling
;
Zhang, Sulin
;
Pan, Qiang
;
Guo, Jiacheng
;
Li, Ni
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
Geriatric Nutritional Risk Index is an effective prognostic predictor for metastatic/recurrent or unresectable esophageal cancer receiving immunotherapy
期刊论文
OAI收割
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2025, 卷号: 16, 期号: 1, 页码: 22
作者:
Wang, Bei
;
Wang, Zixuan
;
Xu, Chuanhai
;
Wang, Yueqin
;
Gao, Honglan
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收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Geriatric Nutritional Risk Index (GNRI)
esophageal squamous cell carcinoma (ESCC)
immune checkpoint inhibitors (ICIs)
programmed cell death ligand 1 (PD-L1)
Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21
作者:
Sui, Qibang
;
Zhou, Yuanyang
;
Li, Manjia
;
Wang, Dan
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/25
Synthetic lethal
MSI tumors
WRN inhibitors
Triazolo-pyrimidine derivatives
Coupling coordination between carbon storage protection in alpine wetlands and SDGs: A case study of the Qinghai-Tibet Plateau, China
期刊论文
OAI收割
JOURNAL OF CLEANER PRODUCTION, 2024, 卷号: 483, 页码: 144260
作者:
Liu, Yuanxin
;
Zhao, Mingyue
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收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/01/17
Wetland change
Carbon storage
Sustainable development goals
Multi-scenario simulation
PLUS model
InVEST
FAPM: functional annotation of proteins using multimodal models beyond structural modeling
期刊论文
OAI收割
BIOINFORMATICS, 2024, 卷号: 40, 期号: 12, 页码: 12
作者:
Xiang, Wenkai
;
Xiong, Zhaoping
;
Chen, Huan
;
Xiong, Jiacheng
;
Zhang, Wei
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2025/01/14
GENNDTI: Drug-Target Interaction Prediction Using Graph Neural Network Enhanced by Router Nodes
期刊论文
OAI收割
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2024, 卷号: 28, 期号: 12, 页码: 7588-7598
作者:
Yang, Beiyuan
;
Liu, Yule
;
Wu, Junfeng
;
Bai, Fang
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/01/14
DTI
interpretability
graph enhancement
prior knowledge
graph neural network
DTI
interpretability
graph enhancement
prior knowledge
graph neural network
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Wang, Xudong
;
Xiong, Liwei
;
Zhu, Ying
;
Liu, Sixiu
;
Zhao, Wenfeng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/25