中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共30条,第1-10条 帮助

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Spatial Distribution of Critical Metals and Chemostratigraphy in Co-Rich Ferromanganese Nodules in the Northwestern Pacific Ocean 期刊论文  OAI收割
JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS, 2024, 卷号: 129, 期号: 10, 页码: 15
作者:  
Ren, Jiangbo;  Yang, Yong;  Yu, Miao;  Liu, Jiancheng;  Luo, Shuaijie
  |  收藏  |  浏览/下载:7/0  |  提交时间:2025/04/01
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:  
Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli
  |  收藏  |  浏览/下载:57/0  |  提交时间:2021/04/26
Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188
作者:  
Liang, Xiaofei;  Jiang, Zongru;  Huang, Zhenghui;  Li, Feng;  Chen, Cheng
  |  收藏  |  浏览/下载:40/0  |  提交时间:2020/11/26
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文  OAI收割
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  
Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
  |  收藏  |  浏览/下载:88/0  |  提交时间:2019/11/27
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  
Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
  |  收藏  |  浏览/下载:42/0  |  提交时间:2020/05/21
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文  OAI收割
CANCER LETTERS, 2019, 页码: 105-114
作者:  
Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping
  |  收藏  |  浏览/下载:40/0  |  提交时间:2020/07/14
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  
Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
  |  收藏  |  浏览/下载:51/0  |  提交时间:2019/01/11
Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis 期刊论文  OAI收割
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 11, 页码: 2531-2538
作者:  
Wang, Qi;  Hu, Zhenquan;  Li, Xixiang;  Wang, Aoli;  Wu, Hong
  |  收藏  |  浏览/下载:24/0  |  提交时间:2019/12/25
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:  
Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming
  |  收藏  |  浏览/下载:77/0  |  提交时间:2019/12/25
Two new tricycloalternarenes from Hawaiian endophytic fungus Didymella sp FT433 期刊论文  OAI收割
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 36, 页码: 3381-3383
作者:  
Li, Chunshun;  Hu, Zhenquan;  Liu, Qingsong;  Wu, Xiaohua;  Cao, Shugeng
  |  收藏  |  浏览/下载:33/0  |  提交时间:2019/11/11