中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [34]
金属研究所 [2]
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期刊论文 [39]
会议论文 [1]
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2025 [1]
2024 [3]
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Diazonium-based derivatization for enhanced detection of phosphorylated metabolites by LC-MS in cells
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7
作者:
Wang, Yikang
;
Lin, Feifei
;
Zhu, Guozheng
;
Zhou, Xiaoxue
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
Phosphorylated metabolite
Derivatization
Chromatographic separation
Quantitative analysis
LC-MS
C(sp
3
)-H Carbonylative Cyclization of Hydrazones with CO
2
: Synthesis of Pyrazolone Derivatives
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 89, 期号: 24, 页码: 18746-18751
作者:
Wang, Kai
;
Ouyang, Jun
;
Liu, Huan
;
Yin, Lijun
;
Yang, Kuoqi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/01/14
A novel BODIPY-based theranostic agent for
in vivo
fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 页码: 9
作者:
Zhang, Jingjing
;
Ren, Wenming
;
Liu, Xiaohui
;
Chen, Jingjing
;
Zeng, Yuteng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/05/07
A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14
作者:
Yang, Li
;
Gong, Ying
;
Liu, Feifei
;
Chen, Wuhong
;
Wang, Xinran
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/02/19
Hepatitis B virus
Capsid assembly
Phthalazinone derivatives
Apoptosis
A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Protein C-Terminal Tyrosine Conjugation via Recyclable Immobilized BmTYR
期刊论文
OAI收割
ACS OMEGA, 2022, 页码: 8
作者:
Ji, Xingyu
;
Zhu, Nanlin
;
Ma, Yanjie
;
Liu, Jia
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/13
Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14
作者:
Chen, Jingjing
;
He, Huixin
;
Wei, Aihuan
;
Li, Yalei
;
Cheng, Gang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/08/16
PROTAC
Pyrrolopyridone
BRD4 S
Selectivity
Indoles Oxidative Ring-Opening/Cyclization Cascade with the 1,2-Diaminoarenes: Direct Synthesis of 2-Aryl-3-(2-aminoaryl)quinoxalines br
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 87, 期号: 9, 页码: 6347-6351
作者:
Yan, Jianwei
;
Zheng, Linxia
;
Wang, Jiangfei
;
Liu, Xiaomin
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
Indoles Oxidative Ring-Opening/Cyclization Cascade with the 1,2-Diaminoarenes: Direct Synthesis of 2-Aryl-3-(2-aminoaryl)quinoxalines
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 87, 期号: 9, 页码: 6347-6351
作者:
Yan, Jianwei
;
Zheng, Linxia
;
Wang, Jiangfei
;
Liu, Xiaomin
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/21