机构

• 上海药物研究所 [38]
• 金属研究所 [2]
• 化学研究所 [1]
• 数学与系统科学研究院 [1]
• 过程工程研究所 [1]
• 高能物理研究所 [1]
• 更多

采集方式

• OAI收割 [44]
• iSwitch采集 [1]

内容类型

• 期刊论文 [44]
• 会议论文 [1]

发表日期

• 2026 [1]
• 2025 [4]
• 2024 [4]
• 2023 [2]
• 2022 [5]
• 2021 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共45条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 DMetFinder: A novel mass spectrometry analysis tool for comprehensive drug metabolite detection 期刊论文  OAI收割 TALANTA, 2026, 卷号: 298, 页码: 9 作者:  Ke, Wenhao;  Wang, Yingying;  Zeng, Yanping;  Hou, Haiyang;  Zhu, Dafu   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/12/04 DMetFinder  Drug metabolites  LC-MS/MS  Spectrum similarity  Mass defect filter  Isotope pattern   A Hybrid compound H93 treats prostate cancer by directly binding UHRF1 and promoting protein dimerization 期刊论文  OAI收割 COMMUNICATIONS CHEMISTRY, 2025, 卷号: 8, 期号: 1, 页码: 11 作者:  Fu, Yuxin;  Jiang, Longying;  Xie, Guojian;  Peng, Yuchong;  Fu, Yongming   |  收藏  |  浏览/下载：4/0  |  提交时间：2026/01/28 Design, synthesis, and biological evaluation of KDM5B degraders against hematologic malignancy cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Liu, Xiaowen;  Li, Jiarong;  Guo, Yihao;  Xie, Zhicheng;  Geng, Meiyu   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/12/04 KDM5B  PROTAC  TPD  Hematological malignancy   Fine structural design of 3βHSD1 inhibitors for prostate cancer 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 26, 页码: 12 作者:  He, Dongyin;  Zhang, Luyao;  Yu, Leiye;  Zhang, Yuhang;  Chen, Jingjing   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/09/09 prostate cancer  drug development  AlphaFold  molecular simulations  3 beta 3HSD1   Diazonium-based derivatization for enhanced detection of phosphorylated metabolites by LC-MS in cells 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7 作者:  Wang, Yikang;  Lin, Feifei;  Zhu, Guozheng;  Zhou, Xiaoxue   |  收藏  |  浏览/下载：54/0  |  提交时间：2025/04/01 Phosphorylated metabolite  Derivatization  Chromatographic separation  Quantitative analysis  LC-MS   C(sp3)-H Carbonylative Cyclization of Hydrazones with CO2: Synthesis of Pyrazolone Derivatives 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 89, 期号: 24, 页码: 18746-18751 作者:  Wang, Kai;  Ouyang, Jun;  Liu, Huan;  Yin, Lijun;  Yang, Kuoqi   |  收藏  |  浏览/下载：50/0  |  提交时间：2025/01/14 Analysis of near-well hydraulic fracture propagation behavior in inhomogeneous deep-sea hydrate-bearing-sediments 期刊论文  OAI收割 GEOENERGY SCIENCE AND ENGINEERING, 2024, 卷号: 242, 页码: 15 作者:  Liu, Jinxin;  Yu, Yongping;  Ma, Xiaolong;  Sun, Youhong;  Li, Bing   |  收藏  |  浏览/下载：24/0  |  提交时间：2025/06/27 Inhomogeneous hydrate reservoir  Disseminated hydrates  Extended finite element method  Hydraulic fracturing   A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 页码: 9 作者:  Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng   |  收藏  |  浏览/下载：55/0  |  提交时间：2024/05/07 A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14 作者:  Yang, Li;  Gong, Ying;  Liu, Feifei;  Chen, Wuhong;  Wang, Xinran   |  收藏  |  浏览/下载：91/0  |  提交时间：2024/02/19 Hepatitis B virus  Capsid assembly  Phthalazinone derivatives  Apoptosis   A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8 作者:  Chen, Wuhong;  Gong, Ying;  Long, Guozhang;  Wang, Xinran;  Yang, Yurong   |  收藏  |  浏览/下载：68/0  |  提交时间：2023/10/17 HBV  Capsid assembly modulators  Prodrug  Hepatitis B surface antigen