机构

• 上海药物研究所 [8]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2023 [1]
• 2022 [3]
• 2021 [2]
• 2020 [2]

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15 作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 Betulinic acid  ROR & gamma  Target identification  Rationale structure optimization  Anti-tumor effects  antagonists   General Pharmacological Activation Mechanism of K+ Channels Bypassing Channel Gates 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15 作者:  Liu, Shijie;  Guo, Peipei;  Wang, Kun;  Zhang, Shaoying;  Li, Ya   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/08/30 DNA-encoded focused indazole library synthesis by a palladium- mediated C-N(sp(2)) cross-coupling reaction between DNA-linked (hetero)aryl halides and aromatic nitrogen heterocycles 期刊论文  OAI收割 TETRAHEDRON LETTERS, 2022, 卷号: 96, 页码: 6 作者:  Yang, Juan;  Xia, Shengdi;  Liu, Jiaxiang;  Yu, Zikun;  Mei, Lianghe   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/08/16 Inhibiting Hvl channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects 期刊论文  OAI收割 CELL RESEARCH, 2022, 卷号: 32, 期号: 5, 页码: 461 作者:  Zhang Qiansen;  Ren Yimin;  Mo Yiqing;  Guo Peipei;  Liao Ping   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/05/22 Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12 作者:  Ding, Hong;  Pei, Yuan;  Li, Yuanqing;  Xu, Wen;  Mei, Lianghe   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Epigenetics  Histone acetyltransferase  P300/CBP  Ovarian cancer   Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles 期刊论文  OAI收割 PHARMACEUTICAL RESEARCH, 2021, 页码: 22 作者:  Han, Sifei;  Mei, Lianghe;  Quach, Tim;  Porter, Chris;  Trevaskis, Natalie   |  收藏  |  浏览/下载：46/0  |  提交时间：2021/11/04 conjugate  lipid  lymphatic  pharmacokinetics  prodrug   Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 19, 页码: 10972-10983 作者:  Ma, Yuqin;  Luo, Qichao;  Fu, Jie;  Che, Yanxin;  Guo, Fei   |  收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24 Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1337-1360 作者:  Yang, Yaxi;  Zhang, Rukang;  Li, Zhaojun;  Mei, Lianghe;  Wan, Shili   |  收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01