中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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高能物理研究所 [28]
近代物理研究所 [16]
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期刊论文 [116]
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/29
Discovery of YFJ-36: Design, Synthesis, and Antibacterial Activities of Catechol-Conjugated β-Lactams against Gram-Negative Bacteria
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Liu, Fangjun
;
Kou, Qunhuan
;
Li, Hongyuan
;
Cao, Yangzhi
;
Chen, Meng
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/22
Distribution, chemical, and molecular composition of high and low molecular weight humic-like substances in ambient aerosols
期刊论文
OAI收割
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2024, 卷号: 24, 期号: 6, 页码: 3769-3783
作者:
Fan, Xingjun
;
Cheng, Ao
;
Yu, Xufang
;
Cao, Tao
;
Chen, Dan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/09/12
Climate-shaped vegetation dominated the spatial pattern of the Bowen ratio over terrestrial ecosystems in China
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 344, 页码: 109816
作者:
Sun, Mingyu
;
Yu, Guirui
;
Chen, Zhi
;
Hao, Tianxiang
;
Yang, Meng
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2024/04/08
Bowen ratio
Heat flux
Sensible heat
Eddy covariance
Spatial patterns
Energy partitioning
Climate-shaped vegetation dominated the spatial pattern of the Bowen ratio over terrestrial ecosystems in China
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 344
作者:
Sun, Mingyu
;
Yu, Guirui
;
Chen, Zhi
;
Hao, Tianxiang
;
Yang, Meng
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/27
Ecosystem responses dominate the trends of annual gross primary productivity over terrestrial ecosystems of China during 2000-2020
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2023, 卷号: 343, 页码: 109758
作者:
Zhu, Xian-Jin
;
Yu, Gui-Rui
;
Chen, Zhi
;
Zhang, Wei-Kang
;
Han, Lang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/12/04
Carbon cycles
Eddy covariance
Terrestrial ecosystems
Machine learning
Ecosystem responses
Solar wind dynamic pressure enhancements in upstream region near Mars
期刊论文
OAI收割
ICARUS, 2023, 卷号: 406, 页码: 12
作者:
Zhao, Dan
;
Guo, Jianpeng
;
Hong, Yichun
;
Meng, Weiduo
;
Huang, Hui
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/02
Heliosphere
Solar wind
Enhanced energization of plume ions around Mars from interplanetary shocks
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2023, 卷号: 679, 页码: 8
作者:
He, Linxia
;
Guo, Jianpeng
;
Zhang, Fan
;
Lin, Haibo
;
Chen, Yan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/01/22
shock waves
acceleration of particles
planets and satellites: individual: Mars
planets and satellites: atmospheres
methods: observational