机构

• 上海药物研究所 [10]
• 中国科学院大学 [1]

采集方式

• OAI收割 [10]
• iSwitch采集 [1]

内容类型

• 期刊论文 [11]

发表日期

• 2022 [2]
• 2021 [2]
• 2019 [1]
• 2018 [2]
• 2016 [3]
• 2015 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Leveraging Protein Dynamics to Identify Functional Sites Models 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 卷号: 62, 期号: 14, 页码: 3331-3345 作者:  Zhu, Fei;  Yang, Sijie;  Meng, Fanwang;  Zheng, Yuxiang;  Ku, Xin   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/11/11 Leveraging Protein Dynamics to Identify Functional Phosphorylation Sites using Deep Learning Models 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 页码: 15 作者:  Zhu, Fei;  Yang, Sijie;  Meng, Fanwang;  Zheng, Yuxiang;  Ku, Xin   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125 作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao   |  收藏  |  浏览/下载：72/0  |  提交时间：2022/01/04 Drug design targeting active posttranslational modification protein isoforms 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2021, 卷号: 41, 期号: 3, 页码: 1701-1750 作者:  Meng, Fanwang;  Liang, Zhongjie;  Zhao, Kehao;  Luo, Cheng   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/22 Allosteric Inhibitor  Covalent Inhibitor  Posttranslational Modifications  Precision Medicine  Protac Protein Degradation  Protein‐  Protein Interactions  Ptm Protein Isoforms  Rational Drug Design   The dynamic conformational landscape of the protein methyltransferase SETD8 期刊论文  OAI收割 ELIFE, 2019, 卷号: 8, 页码: 76 作者:  Chen, Shi;  Wiewiora, Rafal P.;  Meng, Fanwang;  Babault, Nicolas;  Ma, Anqi   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 Machine Learning Methods in Precision Medicine Targeting Epigenetics Diseases 期刊论文  OAI收割 Current pharmaceutical design, 2018 作者:  Fan, Shijie;  Chen, Yu;  Luo, Cheng;  Meng, Fanwang   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Machine Learning Methods in Precision Medicine Targeting Epigenetic Diseases 期刊论文  OAI收割 CURRENT PHARMACEUTICAL DESIGN, 2018, 卷号: 24, 期号: 34, 页码: 3998-4006 作者:  Fan, Shijie;  Chen, Yu;  Luo, Cheng;  Meng, Fanwang   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Machine learning  precision medicine  epigenetics  deep learning  genome  Human Genome Project (HGP)   Discovery of 3-(5 '-substituted)-benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1h-indazoles as potent fibroblast growth factor receptor inhibitors: design, synthesis, and biological evaluation 期刊论文  iSwitch采集 Journal of medicinal chemistry, 2016, 卷号: 59, 期号: 14, 页码: 6690-6708 作者:  Yan, Wei;  Wang, Xinyi;  Dai, Yang;  Zhao, Bin;  Yang, Xinying 收藏  |  浏览/下载：29/0  |  提交时间：2019/05/09 Discovery of 3-(5 '-Substituted)-Benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors: Design, Synthesis, and Biological Evaluation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 14, 页码: 6690-6708 作者:  Yan, Wei;  Wang, Xinyi;  Dai, Yang;  Zhao, Bin;  Yang, Xinying   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 3, 页码: 527-534 作者:  Chen, Shijie;  Li, Linjuan;  Chen, Yantao;  Hu, Junchi;  Liu, Jingqiu   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08