机构

• 上海药物研究所 [6]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2024 [1]
• 2018 [1]
• 2015 [2]
• 2014 [1]
• 2012 [1]

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 9, 页码: E2001-E2009 作者:  Meng, Huyan;  Liu, Zhen;  Li, Xingyan;  Wang, Huibing;  Jin, Taijie   |  收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 RIPK1  death domain  dimerization  necroptosis  RIPK1-dependent apoptosis   G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L 期刊论文  OAI收割 ELIFE, 2015, 卷号: 4 作者:  Zhang, Tao;  Dong, Kangyun;  Liang, Wei;  Xu, Daichao;  Xia, Hongguang   |  收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 Activation of Necroptosis in Multiple Sclerosis 期刊论文  OAI收割 CELL REPORTS, 2015, 卷号: 10, 期号: 11, 页码: 1836-1849 作者:  Ofengeim, Dimitry;  Ito, Yasushi;  Najafov, Ayaz;  Zhang, Yaoyang;  Shan, Bing   |  收藏  |  浏览/下载：46/0  |  提交时间：2019/01/08 2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-jB signaling by inhibiting Janus kinase 2 and IjB kinase 期刊论文  OAI收割 CANCER SCIENCE, 2014, 卷号: 105, 期号: 4, 页码: 473-480 作者:  Kuang, Shan;  Qi, Chunting;  Liu, Jiawei;  Sun, Xiaoxiao;  Zhang, Qing   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 2-Methoxystypandrone  anticancer drug  Janus kinase 2  signal transducer and activator of transcription 3 pathway  natural compound  tumor necrosis factor-  nuclear factor-B pathway   Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2012, 卷号: 84, 期号: 4, 页码: 468-476 作者:  Gu, Yuan;  Qi, Chunting;  Sun, Xiaoxiao;  Ma, Xiuquan;  Zhang, Haohao   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Arctigenin  Glucose deprivation  Tumor cell death  ATP levels  ROS generation