中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Targeting QPCTL: An Emerging Therapeutic Opportunity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 2, 页码: 929-943
作者:
Yu, Lei
;
Sun, Yaoliang
;
Xie, Longyan
;
Tan, Xiao
;
Wang, Ping
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 68, 期号: 1, 页码: 753-775
作者:
Zhang, Qian
;
He, Yingqi
;
Rao, Danni
;
He, Rui
;
Yu, Lei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/02/28
Revealing the adaptation mechanism of different color morphs of sea cucumber
Apostichopus
japonicus
to light intensities from the perspective of metabolomics
期刊论文
OAI收割
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2024, 卷号: 52, 页码: 11
作者:
Liu, Bohong
;
Liu, Shilin
;
Sun, Lina
;
Xing, Lili
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/20
Sea cucumber
Metabolism
Light intensities
Environmental adaptation
Ecological function
Zn2+enhanced the anti-breast cancer activity of fucoidan based nanoparticles by activating the cGAS-STING pathway
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2024, 卷号: 500, 页码: 13
作者:
Xue, Pengyu
;
Wang, Yinghan
;
Wang, Xuefei
;
Zhou, Shilin
;
Wu, Xiaochen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/20
Breast
Fucoidan
Resveratrol
cGAS-STING
Zn 2+
Population genomic analysis reveals a polygenic sex determination system in
Apostichopus japonicus
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 10, 页码: 16
作者:
Jiang, Chunxi
;
Liu, Shilin
;
Yang, Yujia
;
Cui, Wei
;
Xu, Shuai
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/20
Importance of the ECM-receptor interaction for adaptive response to hypoxia based on integrated transcription and translation analysis
期刊论文
OAI收割
MOLECULAR ECOLOGY, 2024, 页码: 19
作者:
Huo, Da
;
Liu, Shilin
;
Zhang, Libin
;
Yang, Hongsheng
;
Sun, Lina
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/06/04
Apostichopus japonicus
ribosome profiling
RNA-seq
transcriptional regulation
translational efficiency
translational regulation
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/05/07
Transcriptome analysis of purple and green
Apostichopus japonicus
reared under different breeding environments
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2024, 卷号: 11, 页码: 11
作者:
Liu, Bohong
;
Xing, Lili
;
Liu, Shilin
;
Sun, Lina
;
Su, Fang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/06/04
Apostichopus japonicus
transcriptome
body color
breeding environment
differentially expressed genes
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent