中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共183条,第1-10条 帮助

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Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10111-10127
作者:  
Deng, Yanan;  Yang, Shiling;  Xu, Hesong;  Ding, Xiyao;  Xu, Ying
  |  收藏  |  浏览/下载:27/0  |  提交时间:2025/06/23
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:  
Hu, Linghao;  Xu, Hesong;  Xu, Ye;  Chen, Haowen;  Jiang, Hanrui
  |  收藏  |  浏览/下载:26/0  |  提交时间:2025/04/01
A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands 期刊论文  OAI收割
NATURE METHODS, 2024, 页码: 17
作者:  
Li, Kejia;  Chen, Shijie;  Wang, Keyun;  Wang, Yan;  Xue, Lianji
  |  收藏  |  浏览/下载:36/0  |  提交时间:2025/01/14
Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 14, 页码: 12184-12204
作者:  
Zhou, Zhenfei;  Huang, Siqi;  Fan, Shijie;  Li, Xueyuan;  Wang, Chengyu
  |  收藏  |  浏览/下载:17/0  |  提交时间:2024/08/22
Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase 期刊论文  OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:  
Zhang, Huimin;  Xu, Dounan;  Huang, Hongchan;  Jiang, Hao;  Hu, Linghao
  |  收藏  |  浏览/下载:46/0  |  提交时间:2024/05/07
Discovery of GPX4 inhibitors through FP-based high-throughput screening 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:  
Cao, Yu;  Wu, Bin;  Xu, Ying;  Wang, Mingchen;  Wu, Xinyu
  |  收藏  |  浏览/下载:70/0  |  提交时间:2024/02/27
PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma 期刊论文  OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:  
Tao, Hongru;  Jin, Chen;  Zhou, Liyuan;  Deng, Zhenzhong;  Li, Xiao
  |  收藏  |  浏览/下载:54/0  |  提交时间:2024/04/09
Rational Design and Synthesis of Novel Benzimidazole Derivatives as Potential β-Glucosidase Inhibitors 期刊论文  OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 卷号: 21, 期号: 13, 页码: 2674-2683
作者:  
Liu, Xu;  Sun, Ge;  Li, Fengxing;  Feng, Xia;  Jia, Tongguan
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/11/05
The effect of cave ventilation on carbon and oxygen isotopic fractionation between calcite and drip water 期刊论文  OAI收割
Science of The Total Environment, 2024, 卷号: 915, 页码: 169967
作者:  
Yina Lyu;  Weijun Luo;  Guangneng Zeng;  Yanwei Wang;  Jia Chen
  |  收藏  |  浏览/下载:25/0  |  提交时间:2025/03/05
Methane sink of subterranean space in an integrated atmosphere-soil-cave system 期刊论文  OAI收割
Environmental Research, 2024, 卷号: 252, 页码: 118904
作者:  
Guangneng Zeng;  Wangbiao Lu;  Yanwei Wang;  Haijun Peng;  Ping Chen
  |  收藏  |  浏览/下载:20/0  |  提交时间:2025/03/03